使用光学相干断层扫描血管造影术评估斜视手术后黄斑血管密度变化
Evaluation of macular vessel density changes after strabismus surgery using optical coherence tomography angiography.
作者信息
Vagge Aldo, Nucci Paolo, Ferro Desideri Lorenzo, Testa Valeria, Scaramuzzi Matteo, Siccardi Gabriele, Bonsignore Francesco, Serafino Massimiliano, Traverso Carlo E
机构信息
IRCCS Ospedale Policlinico San Martino, Genova, Italy; Università di Genova, DiNOGM, Italy I.
DISCCO, University of Milan, Milan, Italy.
出版信息
J AAPOS. 2022 Apr;26(2):71.e1-71.e4. doi: 10.1016/j.jaapos.2021.11.011. Epub 2022 Mar 18.
PURPOSE
To compare retinal vessel density before and after strabismus surgery using swept-source optical coherence tomography angiography (SS-OCTA).
METHODS
In this longitudinal, single-arm pilot study, vascular density in the deep capillary plexus (DCP), superficial retinal capillary plexus (SCP) and choriocapillaris layer (CCL) in consecutive subjects undergoing strabismus surgery was assessed using SS-OCTA preoperatively (T0), on the first day postoperatively (POD1), and 30 days postoperatively (POD30).
RESULTS
A total of 92 eyes of 56 patients (54% males) were included. Mean patient age was 41.1 ± 22.7. OCT vascular density of the DCP was 50.20 ± 5.57 at T0, 52.74 ± 4.77 at POD1, and 50.92 ± 4.58 at POD30. The differences were statistically significant for T0 versus POD1 (P < 0.05). Vascular density of the CCL was 50.72 ± 4.80 at T0, 53.59 ± 3.65 at POD1, and 51.39 ± 4.64 at POD30. The differences were statistically significant for T0 versus POD1 (P < 0.05). No significant differences were found in SCP (P > 0.05).
CONCLUSIONS
Transitory hemodynamic changes can occur in the DCP and in the CCL following muscle recession procedures.
目的
使用扫频源光学相干断层扫描血管造影（SS-OCTA）比较斜视手术前后的视网膜血管密度。
方法
在这项纵向单臂试点研究中，对连续接受斜视手术的受试者，在术前（T0）、术后第1天（POD1）和术后30天（POD30）使用SS-OCTA评估其深层毛细血管丛（DCP）、视网膜浅层毛细血管丛（SCP）和脉络膜毛细血管层（CCL）的血管密度。
结果
共纳入56例患者的92只眼（男性占54%）。患者平均年龄为41.1±22.7岁。DCP的OCT血管密度在T0时为50.20±5.57，在POD1时为52.74±4.77，在POD30时为50.92±4.58。T0与POD1之间的差异具有统计学意义（P<0.05）。CCL的血管密度在T0时为50.72±4.80，在POD1时为53.59±3.65，在POD30时为51.39±4.64。T0与POD1之间的差异具有统计学意义（P<0.05）。SCP未发现显著差异（P>0.05）。
结论
肌肉后徙手术后，DCP和CCL可能会发生短暂的血流动力学变化。
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