Vagge Aldo, Nucci Paolo, Ferro Desideri Lorenzo, Testa Valeria, Scaramuzzi Matteo, Siccardi Gabriele, Bonsignore Francesco, Serafino Massimiliano, Traverso Carlo E
IRCCS Ospedale Policlinico San Martino, Genova, Italy; Università di Genova, DiNOGM, Italy I.
DISCCO, University of Milan, Milan, Italy.
J AAPOS. 2022 Apr;26(2):71.e1-71.e4. doi: 10.1016/j.jaapos.2021.11.011. Epub 2022 Mar 18.
To compare retinal vessel density before and after strabismus surgery using swept-source optical coherence tomography angiography (SS-OCTA).
In this longitudinal, single-arm pilot study, vascular density in the deep capillary plexus (DCP), superficial retinal capillary plexus (SCP) and choriocapillaris layer (CCL) in consecutive subjects undergoing strabismus surgery was assessed using SS-OCTA preoperatively (T0), on the first day postoperatively (POD1), and 30 days postoperatively (POD30).
A total of 92 eyes of 56 patients (54% males) were included. Mean patient age was 41.1 ± 22.7. OCT vascular density of the DCP was 50.20 ± 5.57 at T0, 52.74 ± 4.77 at POD1, and 50.92 ± 4.58 at POD30. The differences were statistically significant for T0 versus POD1 (P < 0.05). Vascular density of the CCL was 50.72 ± 4.80 at T0, 53.59 ± 3.65 at POD1, and 51.39 ± 4.64 at POD30. The differences were statistically significant for T0 versus POD1 (P < 0.05). No significant differences were found in SCP (P > 0.05).
Transitory hemodynamic changes can occur in the DCP and in the CCL following muscle recession procedures.
使用扫频源光学相干断层扫描血管造影（SS-OCTA）比较斜视手术前后的视网膜血管密度。
在这项纵向单臂试点研究中，对连续接受斜视手术的受试者，在术前（T0）、术后第1天（POD1）和术后30天（POD30）使用SS-OCTA评估其深层毛细血管丛（DCP）、视网膜浅层毛细血管丛（SCP）和脉络膜毛细血管层（CCL）的血管密度。
共纳入56例患者的92只眼（男性占54%）。患者平均年龄为41.1±22.7岁。DCP的OCT血管密度在T0时为50.20±5.57，在POD1时为52.74±4.77，在POD30时为50.92±4.58。T0与POD1之间的差异具有统计学意义（P<0.05）。CCL的血管密度在T0时为50.72±4.80，在POD1时为53.59±3.65，在POD30时为51.39±4.64。T0与POD1之间的差异具有统计学意义（P<0.05）。SCP未发现显著差异（P>0.05）。
肌肉后徙手术后，DCP和CCL可能会发生短暂的血流动力学变化。
