Shen Yu, Zhao Xin, Zhao Haijian, Chen Ning, Wang Jian, Zhuang Haiwen, Zhang Xiaoyu
Division of Gastrointestinal Surgery, The Affiliated Huai'an hospital of Xuzhou Medical University, Huai'an, Jiangsu, China (mainland).
Med Sci Monit. 2022 Mar 21;28:e935366. doi: 10.12659/MSM.935366.
BACKGROUND The purpose of this study was to determine the safety and efficacy of enteral nutrition in combination with microbial preparations for bowel preparation in elderly patients with colorectal cancer. MATERIAL AND METHODS Were divided 160 patients diagnosed with colorectal cancer into a control group (n=80) and an experimental group (n=80) by random number table method. The control group took the traditional intestinal preparation, and the experimental group took oral enteral nutrition combined with microbial preparations. Both groups were treated by the same medical team. The postoperative recovery, complications, nutritional status, inflammation, and other indicators of the 2 groups were compared. RESULTS The nutritional status of the experimental group was significantly better than that of the control group, the incidence of tissue inflammation and postoperative complications was significantly lower than that of the control group, and the stool test results of patients with postoperative diarrhea were better than those of the control group, and the difference between groups was statistically significant. CONCLUSIONS The intestinal preparation using enteral nutrition combined with microbial preparations can alleviate the systemic inflammatory response in elderly patients, improve the nutritional status, reduce the occurrence of postoperative complications, and facilitate rapid postoperative recovery.
背景 本研究的目的是确定肠内营养联合微生物制剂用于老年结直肠癌患者肠道准备的安全性和有效性。材料与方法 采用随机数字表法将160例确诊为结直肠癌的患者分为对照组(n = 80)和试验组(n = 80)。对照组采用传统肠道准备,试验组采用口服肠内营养联合微生物制剂。两组均由同一医疗团队治疗。比较两组的术后恢复情况、并发症、营养状况、炎症等指标。结果 试验组的营养状况明显优于对照组,组织炎症和术后并发症的发生率明显低于对照组,术后腹泻患者的粪便检测结果优于对照组,组间差异有统计学意义。结论 肠内营养联合微生物制剂进行肠道准备可减轻老年患者的全身炎症反应,改善营养状况,减少术后并发症的发生,促进术后快速恢复。