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术前和术后营养干预对结直肠癌患者治疗结局和生活质量的影响——全面综述。

The Impact of Preoperative and Postoperative Nutritional Interventions on Treatment Outcomes and Quality of Life in Colorectal Cancer Patients-A Comprehensive Review.

机构信息

Department of General and Oncological Surgery, Faculty of Medicine, Medical University of Lodz, 90-213 Lodz, Poland.

出版信息

Medicina (Kaunas). 2024 Sep 27;60(10):1587. doi: 10.3390/medicina60101587.

Abstract

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide, with high morbidity and mortality rates. Nutritional status has emerged as a significant factor influencing the prognosis and survival of CRC patients. This comprehensive literature review examines the role of nutritional support in improving treatment outcomes, including the efficacy of interventions, patient quality of life (QoL), and the modulation of inflammatory responses. The findings suggest that tailored nutritional interventions improve clinical outcomes, enhance QoL, and reduce treatment-related complications, particularly by attenuating inflammation. Furthermore, the review highlights the cost-effectiveness of nutritional strategies and identifies key methods to enhance patient compliance with dietary recommendations. In conclusion, integrating nutritional support into CRC treatment plans is crucial for optimizing clinical management and improving patient well-being.

摘要

结直肠癌(CRC)是全球最常见的癌症之一,具有较高的发病率和死亡率。营养状况已成为影响 CRC 患者预后和生存的重要因素。本综述全面探讨了营养支持在改善治疗结果中的作用,包括干预措施的疗效、患者的生活质量(QoL)以及炎症反应的调节。研究结果表明,个体化的营养干预可改善临床结果、提高生活质量,并减少治疗相关并发症,特别是通过减轻炎症。此外,该综述还强调了营养策略的成本效益,并确定了增强患者对饮食建议依从性的关键方法。总之,将营养支持纳入 CRC 治疗计划对于优化临床管理和改善患者的生活质量至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3c3/11510076/6483348fb1f1/medicina-60-01587-g001.jpg

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