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胃癌治疗的演变 - 系统评价。

Evolution of treatment in gastric cancer- a systematic review.

机构信息

Department of Surgical Oncology, IMS and SUM Hospital, Kalinga Nagar, Bhubaneswar, Odisha, India.

出版信息

J Egypt Natl Canc Inst. 2022 Mar 21;34(1):12. doi: 10.1186/s43046-022-00114-7.

DOI:10.1186/s43046-022-00114-7
PMID:35307789
Abstract

Multimodality is the standard of care in gastric cancer but surgery remains the mainstay of curative treatment. As we are heading towards a more conservative approach for functional preservation without compromising oncological outcomes in all malignancies, the guidelines keeps changing based on various studies.The extent of surgery used to vary between the east and west, with the east performing more radical surgery and the west more reliant on multimodality therapy. This practice has been changing in the recent times.In this article we have reviewed how the treatment protocols of gastric cancer has evolved and modified, highlighting the practice changing trials.

摘要

多模态治疗是胃癌的标准治疗方法,但手术仍然是主要的治愈性治疗方法。随着我们在所有恶性肿瘤中朝着更加保守的功能保留方法发展,以不影响肿瘤学结果,指南不断根据各种研究进行改变。手术的范围在东西方之间有所不同,东方国家进行更激进的手术,而西方国家则更依赖于多模态治疗。这种做法在最近有所改变。本文回顾了胃癌的治疗方案是如何演变和修改的,重点介绍了改变实践的临床试验。

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Evolution of treatment in gastric cancer- a systematic review.胃癌治疗的演变 - 系统评价。
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2
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Eur J Cancer. 2007 Jan;43(2):258-70. doi: 10.1016/j.ejca.2006.10.014. Epub 2006 Dec 19.
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A life-threatening presentation of postgastrectomy exocrine pancreatic insufficiency: A case report.胃切除术后外分泌性胰腺功能不全的危及生命表现:一例报告。
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本文引用的文献

1
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
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Long-Term Outcomes of Laparoscopic Distal Gastrectomy for Locally Advanced Gastric Cancer: The KLASS-02-RCT Randomized Clinical Trial.腹腔镜辅助进展期胃癌根治术的长期疗效:KLASS-02 RCT 随机临床试验。
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Randomized controlled Phase III trial to evaluate omentum preserving gastrectomy for patients with advanced gastric cancer (JCOG1711, ROAD-GC).
胃切除术后清扫的淋巴结数量对胃癌患者生存和复发率的影响:一项多中心回顾性队列研究。
BMC Surg. 2023 Aug 21;23(1):246. doi: 10.1186/s12893-023-02154-9.
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Skin metastases from gastric cancer, a rare entity masquerading as erysipelas: A case report.胃癌皮肤转移,一种伪装成丹毒的罕见病症:病例报告。
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一项评价保留大网膜的胃癌根治术治疗进展期胃癌的随机对照 III 期临床试验(JCOG1711,ROAD-GC)。
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4
Survival outcomes after laparoscopy-assisted distal gastrectomy versus open distal gastrectomy with nodal dissection for clinical stage IA or IB gastric cancer (JCOG0912): a multicentre, non-inferiority, phase 3 randomised controlled trial.腹腔镜辅助与开腹远端胃癌根治术加淋巴结清扫术治疗临床ⅠA 期或ⅠB 期胃癌的生存结局(JCOG0912):一项多中心、非劣效性、Ⅲ期随机对照临床试验。
Lancet Gastroenterol Hepatol. 2020 Feb;5(2):142-151. doi: 10.1016/S2468-1253(19)30332-2. Epub 2019 Nov 19.
5
Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial.腹腔镜与开腹远端胃癌根治术对局部进展期胃癌患者 3 年无病生存率的影响:CLASS-01 随机临床试验。
JAMA. 2019 May 28;321(20):1983-1992. doi: 10.1001/jama.2019.5359.
6
Effect of Laparoscopic Distal Gastrectomy vs Open Distal Gastrectomy on Long-term Survival Among Patients With Stage I Gastric Cancer: The KLASS-01 Randomized Clinical Trial.腹腔镜远端胃切除术与开腹远端胃切除术治疗Ⅰ期胃癌患者的长期生存效果比较:KLASS-01 随机临床试验。
JAMA Oncol. 2019 Apr 1;5(4):506-513. doi: 10.1001/jamaoncol.2018.6727.
7
CRITICS-II: a multicentre randomised phase II trial of neo-adjuvant chemotherapy followed by surgery versus neo-adjuvant chemotherapy and subsequent chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery in resectable gastric cancer.CRITICS-II 研究:新辅助化疗后手术与新辅助化疗及后续放化疗后手术对比新辅助放化疗后手术治疗可切除胃癌的多中心随机 II 期临床试验
BMC Cancer. 2018 Sep 10;18(1):877. doi: 10.1186/s12885-018-4770-2.
8
A feasibility study of laparoscopic total gastrectomy for clinical stage I gastric cancer: a prospective multi-center phase II clinical trial, KLASS 03.腹腔镜全胃切除术治疗临床Ⅰ期胃癌的可行性研究:一项前瞻性多中心Ⅱ期临床试验,KLASS 03。
Gastric Cancer. 2019 Jan;22(1):214-222. doi: 10.1007/s10120-018-0864-4. Epub 2018 Aug 20.
9
Bursectomy versus omentectomy alone for resectable gastric cancer (JCOG1001): a phase 3, open-label, randomised controlled trial.单纯脾切除术与单纯网膜切除术治疗可切除性胃癌(JCOG1001):一项 III 期、开放标签、随机对照临床试验。
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10
Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial.手术和术前化疗后可切除胃癌的化疗与放化疗(CRITICS):一项国际、开放标签、随机 3 期试验。
Lancet Oncol. 2018 May;19(5):616-628. doi: 10.1016/S1470-2045(18)30132-3. Epub 2018 Apr 9.