Lieberman K, Alexander G J, Sechzer J A
Experientia. 1986 Sep 15;42(9):985-7. doi: 10.1007/BF01940701.
Lithium, which is used routinely in the treatment of mania, is composed of two stable isotopes, lithium-7 (92.58%) and lithium-6 (7.42%). Usually there is minimal physiological or biochemical differentiation between isotopes of an element, but lithium is an exception. Data derived from a variety of biochemical and behavioral experiments are reviewed to support this idea. Additionally, the clinical implications of this work are presented.
锂常用于治疗躁狂症,它由两种稳定同位素组成,即锂 - 7(92.58%)和锂 - 6(7.42%)。通常,一种元素的同位素之间在生理或生化方面的差异极小,但锂是个例外。本文综述了来自各种生化和行为实验的数据以支持这一观点。此外,还介绍了这项工作的临床意义。