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那些锂暴露婴儿后来怎么样了?一项针对出生时无畸形儿童的随访研究。

What happened later to the lithium babies? A follow-up study of children born without malformations.

作者信息

Schou M

出版信息

Acta Psychiatr Scand. 1976 Sep;54(3):193-7. doi: 10.1111/j.1600-0447.1976.tb00112.x.

DOI:10.1111/j.1600-0447.1976.tb00112.x
PMID:970196
Abstract

The Lithium Baby Register was founded in 1968 to determine the frequency of abnormalities among children born to mothers who were given lithium during the first trimester of pregnancy. Previous studies have revealed an increased frequency of congenital malformations, possibly due to teratogenic action of lithium. The present report is a questionnaire follow-up of the physical and mental development of lithium children who were not malformed at birth. Sixty lithium children were examined; their siblings, who had not been exposed to lithium during fetal life, served as a control group. The data obtained do not reveal any increased frequency of physical or mental anomalies among the lithium children.

摘要

锂宝宝登记册于1968年设立,旨在确定孕期头三个月服用锂的母亲所生儿童中异常情况的发生率。此前的研究表明先天性畸形的发生率有所增加,这可能是由于锂的致畸作用。本报告是对出生时无畸形的锂暴露儿童身心发育情况的问卷调查随访。对60名锂暴露儿童进行了检查;他们未在胎儿期接触过锂的兄弟姐妹作为对照组。所获得的数据并未显示锂暴露儿童中身体或精神异常的发生率有任何增加。

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Acta Psychiatr Scand. 1976 Sep;54(3):193-7. doi: 10.1111/j.1600-0447.1976.tb00112.x.
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