Bin Waqar Syed Hamza, Rehan Aiman, Salahi Navid, Zhonghua Li, McFarlane Isabel
Internal Medicine, State University of New York Downstate Health Sciences University, New York, USA.
Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Cureus. 2022 Mar 16;14(3):e23219. doi: 10.7759/cureus.23219. eCollection 2022 Mar.
Intracranial plasmacytoma is an exceedingly rare presentation of plasma cell neoplasms. Usually presenting late in the course of the disease, progression from the presentation can be abrupt. Hence, a low threshold to biopsy the lesion should be maintained during diagnostic evaluation. Multiple myeloma workup should also be sent and treated concomitantly along with local treatment. Here, we present a case of extramedullary plasmacytoma of the clivus leading to progressive visual deficits with undiagnosed multiple myeloma requiring pulse steroids, intracranial irradiation, and high-dose chemotherapy with improvement in symptoms.
颅内浆细胞瘤是浆细胞肿瘤极为罕见的一种表现形式。通常在疾病进程后期出现，起病后进展可能迅速。因此，在诊断评估过程中，对于该病变进行活检的阈值应保持较低。还应进行多发性骨髓瘤检查，并在进行局部治疗的同时进行相应治疗。在此，我们报告一例斜坡髓外浆细胞瘤导致进行性视力减退，同时伴有未确诊的多发性骨髓瘤，患者接受了冲击剂量类固醇、颅内放疗和大剂量化疗，症状有所改善。
