Bordt J, Belkien L, Zenzes M T, Hanker J P, Nieschlag E, Schneider H P
Geburtshilfe Frauenheilkd. 1986 Jul;46(7):416-21. doi: 10.1055/s-2008-1026655.
Between September 1, 1983 and June 15, 1984 69 patients were treated by in-vitro fertilization as part of a clinical research project. The scientific questions were aimed at optimizing the principal methodological aspects of the new technique. One hundred and sixty-nine follicle punctures were performed under laparoscopic or ultrasonographic control. A total of 207 preovulatory oocytes were obtained, 57 of which were transferred to the uterus as cleaving embryos following in-vitro fertilization. Seven clinical pregnancies were diagnosed. Two resulted in spontaneous abortion in the fifth and sixth week of gestation, the remaining five as three single and two twin births. The infrastructure of reproduction medicine has been broadened successfully within a short time. Considering the results of current clinical and experimental research, the efficiency of the methods used is likely to be improved.
1983年9月1日至1984年6月15日期间，作为一项临床研究项目的一部分，69名患者接受了体外受精治疗。科学问题旨在优化新技术的主要方法学方面。在腹腔镜或超声控制下进行了169次卵泡穿刺。共获得207个排卵前卵母细胞，其中57个在体外受精后作为分裂胚胎转移到子宫。诊断出7例临床妊娠。其中2例在妊娠第5周和第6周自然流产，其余5例为3例单胎和2例双胎分娩。生殖医学的基础设施在短时间内成功得到了拓展。考虑到当前临床和实验研究的结果，所用方法的效率可能会得到提高。
