Kloss W, Meier-Ewert K, Schäfer H
Fortschr Neurol Psychiatr. 1986 Aug;54(8):267-71. doi: 10.1055/s-2007-1001873.
Symptomatology and sequelae, as well as diagnosis and therapy of the obstructive sleep apnea syndrome are discussed. The Esmarch prosthesis, which we developed for the prosthetic treatment of obstructive sleep apnea syndrome, was tested in 7 patients. Patients were polysomnographically recorded during two sequential nights with and without Esmarch prosthesis. All apnea parameters improved significantly (apnea time by 78%, apnea index by 67% of baseline values). The mean duration of the remaining apnea phases diminished by 31%. Improvement of O2 saturation of haemoglobin and O2 partial pressure in the tissue paralleled that of the apnea parameters. The severely disturbed sleep profile of the patients showed a clear tendency towards normalization. The Esmarch prosthesis is an efficient method for the treatment of the obstructive sleep apnea syndrome.
本文讨论了阻塞性睡眠呼吸暂停综合征的症状学、后遗症以及诊断和治疗方法。我们研发的用于阻塞性睡眠呼吸暂停综合征修复治疗的埃斯马赫假体，在7例患者中进行了测试。在使用和不使用埃斯马赫假体的情况下，对患者进行了连续两晚的多导睡眠图记录。所有呼吸暂停参数均有显著改善（呼吸暂停时间减少78%，呼吸暂停指数降至基线值的67%）。其余呼吸暂停阶段的平均持续时间缩短了31%。血红蛋白氧饱和度和组织中氧分压的改善与呼吸暂停参数的改善情况相似。患者严重紊乱的睡眠模式呈现出明显的正常化趋势。埃斯马赫假体是治疗阻塞性睡眠呼吸暂停综合征的一种有效方法。
