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一例导致胸壁坏死性筋膜炎的高毒力表型病例:一种在印度次大陆出现的单微生物病原体。

A case of hypervirulent phenotype causing necrotizing fasciitis of chest wall: A mono-microbial entity emerging in the Indian subcontinent.

作者信息

Dasgupta Rituparna, Das Arghya

机构信息

Department of General Surgery, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.

Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Family Med Prim Care. 2022 Jan;11(1):376-378. doi: 10.4103/jfmpc.jfmpc_1023_21. Epub 2022 Jan 31.

Abstract

Necrotizing fasciitis of the chest wall or upper torso is a rare clinical entity. Monomicrobial as a causative agent of necrotizing fasciitis is far less common than the polymicrobial etiology. Here, we report a case of community-onset pyogenic necrotizing fasciitis caused by in an immunocompetent male of tribal background from the rural area of Jharkhand, India. The hypermucoviscous phenotype of the bacterium causing necrotizing fasciitis has been infrequently reported from the Indian subcontinent to date. The existence of multidrug resistant trait in the hypervirulent pathotype poses a unique challenge in treatment in such a case and emerges as a critical community health problem requiring prompt attention of the public health stakeholders. Thus, there is a need for widespread awareness for proper protocols in antimicrobial usage, infection control, early diagnosis, and prompt treatment.

摘要

胸壁或上半身的坏死性筋膜炎是一种罕见的临床病症。作为坏死性筋膜炎致病原的单一微生物远比多微生物病因少见。在此,我们报告一例社区获得性化脓性坏死性筋膜炎病例,该病例由[未提及细菌名称]引起,患者为一名来自印度贾坎德邦农村地区、具有部落背景的免疫功能正常男性。迄今为止,印度次大陆鲜有关于引起坏死性筋膜炎的细菌高黏液表型的报道。高毒力致病型中多重耐药特性的存在给此类病例的治疗带来了独特挑战,并成为一个需要公共卫生利益相关者迅速关注的关键社区健康问题。因此,有必要广泛提高对抗菌药物使用、感染控制、早期诊断和及时治疗等适当方案的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0d4/8930121/f9235ea3c305/JFMPC-11-376-g001.jpg

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