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The diagnostic potential of the iron-regulatory hormone hepcidin.

作者信息

Armitage Andrew E, Drakesmith Hal

机构信息

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

Haematology Theme, Oxford Biomedical Research Centre, Oxford, United Kingdom.

出版信息

Hemasphere. 2019 Jun 30;3(Suppl). doi: 10.1097/HS9.0000000000000236. eCollection 2019 Jun.

DOI:10.1097/HS9.0000000000000236
PMID:35309797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8925696/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee0/8925696/57672709879b/hs9-3-0100-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee0/8925696/57672709879b/hs9-3-0100-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bee0/8925696/57672709879b/hs9-3-0100-g001.jpg

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The diagnostic potential of the iron-regulatory hormone hepcidin.铁调节激素铁调素的诊断潜力。
Hemasphere. 2019 Jun 30;3(Suppl). doi: 10.1097/HS9.0000000000000236. eCollection 2019 Jun.
2
[Hepcidin, the negative regulator of iron absorbtion].[铁调素，铁吸收的负调节因子]
Orv Hetil. 2004 Jul 25;145(30):1549-52.
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The iron-regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney.铁调节肽激素铁调素：在哺乳动物肾脏中的表达及细胞定位
J Endocrinol. 2005 Feb;184(2):361-70. doi: 10.1677/joe.1.05729.
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J Clin Diagn Res. 2013 Aug;7(8):1767-71. doi: 10.7860/JCDR/2013/6420.3273. Epub 2013 Aug 1.
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Clinical Immunoassay for Human Hepcidin Predicts Iron Deficiency in First-Time Blood Donors.临床免疫测定人铁调素可预测初次献血者缺铁。
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本文引用的文献

1
Hypoxia attenuates inflammation-induced hepcidin synthesis during experimental human endotoxemia.缺氧减弱实验性人类内毒素血症期间炎症诱导的铁调素合成。
Haematologica. 2019 Jun;104(6):e230-e232. doi: 10.3324/haematol.2018.202796. Epub 2019 Jan 17.
2
The opposing effects of acute inflammation and iron deficiency anemia on serum hepcidin and iron absorption in young women.急性炎症和缺铁性贫血对年轻女性血清铁调素和铁吸收的相反作用。
Haematologica. 2019 Jun;104(6):1143-1149. doi: 10.3324/haematol.2018.208645. Epub 2019 Jan 10.
3
Provisional standardization of hepcidin assays: creating a traceability chain with a primary reference material, candidate reference method and a commutable secondary reference material.
暂定铁调素检测方法的标准化：建立溯源链，使用一级参考物质、候选参考方法和可互换的二级参考物质。
Clin Chem Lab Med. 2019 May 27;57(6):864-872. doi: 10.1515/cclm-2018-0783.
4
An intensified training schedule in recreational male runners is associated with increases in erythropoiesis and inflammation and a net reduction in plasma hepcidin.在业余男性跑步者中，强化训练计划与红细胞生成和炎症增加以及血浆铁调素净减少有关。
Am J Clin Nutr. 2018 Dec 1;108(6):1324-1333. doi: 10.1093/ajcn/nqy247.
5
Transient decrease of serum iron after acute erythropoietin treatment contributes to hepcidin inhibition by ERFE in mice.急性促红细胞生成素治疗后血清铁的短暂降低有助于铁调素在小鼠中被促红细胞生成素释放因子抑制。
Haematologica. 2019 Mar;104(3):e87-e90. doi: 10.3324/haematol.2018.199810. Epub 2018 Sep 28.
6
Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress.红细胞中铁蛋白缺乏导致血清铁缺乏，并由于氧化应激而促进溶血。
Blood. 2018 Nov 8;132(19):2078-2087. doi: 10.1182/blood-2018-04-842997. Epub 2018 Sep 13.
7
Erythroferrone inhibits the induction of hepcidin by BMP6.促红细胞生成素抑制 BMP6 诱导的铁调素表达。
Blood. 2018 Oct 4;132(14):1473-1477. doi: 10.1182/blood-2018-06-857995. Epub 2018 Aug 10.
8
Optimizing diagnostic biomarkers of iron deficiency anemia in community-dwelling Indian women and preschool children.优化社区居住的印度女性和学龄前儿童缺铁性贫血的诊断生物标志物。
Haematologica. 2018 Dec;103(12):1991-1996. doi: 10.3324/haematol.2018.193243. Epub 2018 Aug 9.
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Circulating iron levels influence the regulation of hepcidin following stimulated erythropoiesis.循环铁水平影响刺激红细胞生成后的铁调素调节。
Haematologica. 2018 Oct;103(10):1616-1626. doi: 10.3324/haematol.2017.187245. Epub 2018 Jun 14.
10
Biomarkers of Nutrition for Development (BOND)-Iron Review.营养与发展生物标志物（BOND）-铁评估报告
J Nutr. 2018 Jun 1;148(suppl_1):1001S-1067S. doi: 10.1093/jn/nxx036.