Department of Ophthalmology, Shenzhen People's Hospital, Shenzhen 518000, China.
Department of Ophthalmology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518000, China.
Comput Math Methods Med. 2022 Mar 9;2022:8437066. doi: 10.1155/2022/8437066. eCollection 2022.
In order to analyze changes in retinal vessel flow after small incision lenticule extraction (SMILE).
A total of 32 patients (62 eyes) who underwent SMILE were enrolled in this prospective study. Optical parameters, including vessel density (VD), and perfusion density (PD) of foveal, parafoveal, and perifoveal regions, respectively, were measured before surgery and at 1 day, 1 week, 1 month, and 3 months postoperation. Preoperative parameters and surgical parameters were recorded.
Significant decreases in VD and PD on postoperative day 1 were detected in all quadrants, both in 3 mm and in 6 mm regions ( < 0.001). One month after surgery, VD returned to preoperative levels. None of the preoperative and surgical parameters were significantly correlated with the VD and PD fluctuations (all > 0.05). VD may decrease significantly with regional disparity 1 day after SMILE while recovering at 1 month. Elevation of intraocular pressure due to suction may account for such changes.
分析小切口微透镜取出术（SMILE）后视网膜血管血流的变化。
前瞻性研究共纳入 32 例（62 只眼）接受 SMILE 的患者。分别于术前和术后 1 天、1 周、1 个月、3 个月测量光学生物测量参数，包括黄斑中心凹、旁中心凹和中心凹外区的血管密度（VD）和灌注密度（PD）。记录术前和手术参数。
所有象限（3mm 和 6mm 区域）在术后第 1 天均检测到 VD 和 PD 显著降低（<0.001）。术后 1 个月，VD 恢复到术前水平。术前和手术参数与 VD 和 PD 的波动均无显著相关性（均>0.05）。SMILE 后 1 天，VD 可能因区域差异而显著降低，1 个月后恢复。眼压升高可能与这种变化有关。
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