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老年阵发性心房颤动：基于直线加速器的立体定向心律失常射频消融前瞻性II期试验的全球初步数据。

Paroxysmal Atrial Fibrillation in Elderly: Worldwide Preliminary Data of LINAC-Based Stereotactic Arrhythmia Radioablation Prospective Phase II Trial.

作者信息

Di Monaco Antonio, Gregucci Fabiana, Bonaparte Ilaria, Troisi Federica, Surgo Alessia, Di Molfetta Domenico, Vitulano Nicola, Quadrini Federico, Carbonara Roberta, Martinelli Gaetano, Guida Pietro, Ciliberti Maria Paola, Fiorentino Alba, Grimaldi Massimo

机构信息

Department of Cardiology, General Regional Hospital F. Miulli, Bari, Italy.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

出版信息

Front Cardiovasc Med. 2022 Mar 2;9:832446. doi: 10.3389/fcvm.2022.832446. eCollection 2022.

DOI:10.3389/fcvm.2022.832446
PMID:35310997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8924125/
Abstract

UNLABELLED

Treatment approach for elderly patients with atrial fibrillation (AF) is difficult. The present prospective phase-II trial evaluated LINAC-based stereotactic arrhythmia radioablation safety in this population. The reported data of the first 5 patients worldwide, showed no side effects, absence of AF episodes and without antiarrhythmic drugs.

TRIAL REGISTRATION

ClinicalTrials.gov, identifier: NCT04575662.

摘要

未标注

老年房颤（AF）患者的治疗方法具有挑战性。本前瞻性II期试验评估了基于直线加速器的立体定向心律失常射频消融术在该人群中的安全性。全球首批5例患者的报告数据显示无副作用、无房颤发作且无需抗心律失常药物。

试验注册

ClinicalTrials.gov，标识符：NCT04575662。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d0/8924125/4b9b0ea43544/fcvm-09-832446-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d0/8924125/4b9b0ea43544/fcvm-09-832446-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d0/8924125/4b9b0ea43544/fcvm-09-832446-g0001.jpg

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Jpn J Radiol. 2021 Dec;39(12):1223-1228. doi: 10.1007/s11604-021-01159-9. Epub 2021 Jul 9.
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4
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