Saxén L, Asikainen S, Sandholm L, Kari K
J Clin Periodontol. 1986 Aug;13(7):714-9. doi: 10.1111/j.1600-051x.1986.tb00870.x.
20 patients with juvenile periodontitis (JP) were treated with oral hygiene instruction, scaling and root planing, possibly with flap surgery but with no antibiotics. The patients were monitored after 6 to 12 years. Re-examination revealed that no probing depth of 7 mm or more existed any longer, and that sites with probing depth of 4 to 6 mm had decreased from 237 to 46. The bone loss scores had changed from 18% (range 2.0 to 48.1) to 14% (range 0 to 44.4) and the bleeding on probing scores from 39% (range 0 to 100) to 10% (range 0 to 40). Actinobacillus actinomycetemcomitans (A.a.) had neither been cultivated nor serologically tested at the initial examination. At the re-examination, it was found in 2 patients out of 20 at 5 sites. 7 patients, the 2 with positive cultures included, had elevated titers to A.a. strain Y4 in whole or parotid saliva or both. It is concluded that there is a marked improvement in the periodontal condition of these patients, and that good periodontal health in patients with JP can be reached without antibiotics.
20例青少年牙周炎（JP）患者接受了口腔卫生指导、龈上洁治和根面平整治疗，可能还进行了翻瓣手术，但未使用抗生素。对这些患者进行了6至12年的随访。复查发现，不再存在探诊深度达7mm或更深的情况，探诊深度为4至6mm的部位从237个减少至46个。骨丧失评分从18%（范围2.0至48.1）变为14%（范围0至44.4），探诊出血评分从39%（范围0至100）变为10%（范围0至40）。在初次检查时，伴放线放线杆菌（A.a.）既未培养出来，也未进行血清学检测。在复查时，在20例患者中的2例的5个部位发现了该菌。包括2例培养阳性的患者在内，有7例患者的全唾液或腮腺唾液或两者中抗A.a.菌株Y4的滴度升高。得出的结论是，这些患者的牙周状况有显著改善，并且青少年牙周炎患者不使用抗生素也可实现良好的牙周健康。
