Lindhe J, Liljenberg B
J Clin Periodontol. 1984 Jul;11(6):399-410. doi: 10.1111/j.1600-051x.1984.tb01338.x.
The present investigation was performed to study the effect on localized juvenile periodontitis (LJP) of a treatment program which included tetracycline administration, surgical elimination of inflamed tissues, scaling and root planing, and careful plaque control during healing. Treatment of LJP lesions was carried out on 16 individuals aged 14 to 18 years (JP group). Lesions in first molars and incisors in a group of patients with adult periodontal disease (AP) were treated in an identical manner and served as controls. The presence of angular bony defects adjacent to first molars and incisors was first documented in all patients. Thereafter, a clinical examination was carried out, including assessments of oral hygiene status, gingival conditions, probing depths and attachment levels. The patients were subjected to a treatment program involving administration of tetracycline (250 mg 4 times per day for 2 weeks), removal of granulation tissue after flap elevation, and root curettage. After surgery, the patients were instructed to rinse the mouth with 0.2% chlorhexidine for 2 min twice a day during the first 2 postsurgical weeks. Professional tooth cleaning was carried out once every 3 months during a 5-year period. At 6, 12, 24 and 60 months after surgical treatment, the patients were re-examined regarding oral hygiene, gingival conditions, probing depths and attachment levels. Treatment of LJP lesions resulted in resolution of gingival inflammation, gain of clinical attachment, and refill of bone in angular bony defects. The healing of the lesions of this patient sample was similar to healing observed in patients with AP.
本研究旨在探讨一种治疗方案对局限性青少年牙周炎(LJP)的影响,该方案包括四环素给药、手术切除炎症组织、龈下刮治和根面平整,以及愈合期间仔细的菌斑控制。对16名年龄在14至18岁的个体(JP组)的LJP病变进行治疗。以相同方式治疗一组成人牙周病(AP)患者的第一磨牙和切牙病变,并作为对照。首先记录所有患者第一磨牙和切牙旁的角形骨缺损情况。此后,进行临床检查,包括评估口腔卫生状况、牙龈状况、探诊深度和附着水平。患者接受了一个治疗方案,包括四环素给药(250毫克,每日4次,共2周)、翻瓣后切除肉芽组织和牙根刮治。手术后,指导患者在术后前2周每天用0.2%氯己定漱口2分钟,持续2次。在5年期间,每3个月进行一次专业牙齿清洁。在手术治疗后6、12、24和60个月,对患者进行口腔卫生、牙龈状况、探诊深度和附着水平的复查。LJP病变的治疗导致牙龈炎症消退、临床附着增加以及角形骨缺损处骨组织的再填充。该患者样本病变的愈合情况与AP患者观察到的愈合情况相似。