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针对人胎盘细胞滋养层和合体滋养层的单克隆抗体。

Monoclonal antibodies to cytotrophoblast and syncytiotrophoblast of human placenta.

作者信息

Contractor S F, Sooranna S R

出版信息

J Dev Physiol. 1986 Aug;8(4):277-82.

PMID:3531302
Abstract

Mouse monoclonal antibodies were raised against plasma membranes-enriched fractions of 8-12 week placental villi. Several antibodies were obtained and three of these are described in detail: ED822 reacts with the outer membrane of the syncytiotrophoblast; ED235 reacts with the cytotrophoblast layer; ED341 reacts with the whole trophoblastic layer. Antibodies ED235 and ED341 were useful markers for identification of trophoblast cells in culture.

摘要

制备了针对8至12周胎盘绒毛富含质膜部分的小鼠单克隆抗体。获得了几种抗体，其中三种被详细描述：ED822与合体滋养层的外膜反应；ED235与细胞滋养层反应；ED341与整个滋养层反应。抗体ED235和ED341是培养中滋养层细胞鉴定的有用标志物。

相似文献

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Monoclonal antibodies to cytotrophoblast and syncytiotrophoblast of human placenta.针对人胎盘细胞滋养层和合体滋养层的单克隆抗体。
J Dev Physiol. 1986 Aug;8(4):277-82.
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Identification of antibodies against HAI-1 and integrin alpha6beta4 as immunohistochemical markers of human villous cytotrophoblast.鉴定抗HAI-1和整合素α6β4抗体作为人绒毛细胞滋养层细胞免疫组织化学标志物。
J Histochem Cytochem. 2006 Jul;54(7):745-52. doi: 10.1369/jhc.5A6816.2006. Epub 2006 Feb 22.
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GZ 100, 101, 106, 107, 111, 112, 116, 121: a series of monoclonal antibodies against human trophoblast antigens.
Acta Histochem Suppl. 1990;38:227-31.
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HLA Class I protein expression in the human placenta.人类胎盘中的HLA I类蛋白表达。
Early Pregnancy (Cherry Hill). 2001 Jan;5(1):67-9.
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Ontogeny of the MHC antigens on human trophoblast cells during the first trimester of pregnancy.妊娠头三个月人滋养层细胞上主要组织相容性复合体抗原的个体发生。
J Immunol. 1983 Nov;131(5):2348-55.
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Human placental cells in culture: a panning technique using a trophoblast-specific monoclonal antibody for cell separation.培养中的人胎盘细胞：一种使用滋养层特异性单克隆抗体进行细胞分离的淘选技术。
J Dev Physiol. 1988 Feb;10(1):47-51.
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Cell surface antigens of human trophoblast: definition of an apparently unique system with a monoclonal antibody.人滋养层细胞的细胞表面抗原：用单克隆抗体对一个明显独特系统的定义。
Immunology. 1986 Sep;59(1):135-8.
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Immunohistologic identification of trophoblast populations in early human pregnancy with the use of monoclonal antibodies.
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ED(27) trophoblast-like cells isolated from first-trimester chorionic villi are genetically identical to HeLa cells yet exhibit a distinct phenotype.从孕早期绒毛膜绒毛中分离出的27号胚胎干细胞样细胞与海拉细胞基因相同，但表现出不同的表型。
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Bi-potential behaviour of cytotrophoblasts in first trimester chorionic villi.孕早期绒毛膜绒毛中细胞滋养层细胞的双潜能行为。
Placenta. 2006 Apr-May;27(4-5):367-74. doi: 10.1016/j.placenta.2005.03.006. Epub 2005 Jun 13.

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