Department of Nephrology, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000 Guangxi, Guangxi Zhuang Autonomous Region, China.
Biomed Res Int. 2022 Mar 12;2022:2786147. doi: 10.1155/2022/2786147. eCollection 2022.
The internal thickness of the carotid artery is the vertical distance between the intima of the carotid artery and the middle mold. Its normal thickness is less than 1 mm. It can be used to judge the degree of arteriosclerosis. Under normal circumstances, the change of the internal thickness of the carotid artery is caused by cardiovascular disease. The purpose of this article is to study the relationship between the thickness of the carotid artery and the metabolism of calcium and phosphorus, parathyroid hormone, microinflammatory state, and cardiovascular disease. This article uses ultrasound measurement to measure the IMT of ESRD patients and carotid arteries with normal renal function. The analysis includes blood pressure, blood phosphorus, blood calcium, blood creatinine, blood urea nitrogen, blood sugar, glycosylated hemoglobin, blood lipids, parathyroid hormone, and C reaction. The correlation between clinical indicators includes protein and carotid IMT in ESRD patients which can be used in designing a diagnostic plan for patients through correlation research. The results showed that the carotid artery IMT of ESRD nondialysis patients was 13% thicker than that of those with normal renal function, and it was significantly positively correlated with age, blood pressure, blood phosphorus, glycosylated hemoglobin, and C-reactive protein. The correlation ratio with calcium and phosphorus was about 0.1.
颈内动脉内膜中层厚度是颈内动脉内膜与中层之间的垂直距离。其正常值小于 1mm，可以用来判断动脉硬化的程度。一般情况下，颈内动脉内膜中层厚度的变化与心血管疾病有关。本文旨在研究颈动脉厚度与钙磷代谢、甲状旁腺激素、微炎症状态和心血管疾病的关系。本文采用超声测量的方法测量了肾功能正常和 ESRD 患者的 IMT，分析指标包括血压、血磷、血钙、血肌酐、血尿素氮、血糖、糖化血红蛋白、血脂、甲状旁腺激素和 C 反应蛋白等。对临床指标进行相关性分析，包括肾功能正常和 ESRD 患者的蛋白与颈动脉 IMT 的相关性，可以通过相关性研究为患者制定诊断方案。结果表明，未透析的 ESRD 患者的颈内动脉 IMT 比肾功能正常的患者厚 13%，与年龄、血压、血磷、糖化血红蛋白和 C 反应蛋白呈显著正相关，与钙磷的相关系数约为 0.1。
