Shibasaki Ikuko, Ouchi Motoshi, Fukuda Taira, Tsuchiya Go, Ogawa Hironaga, Takei Yusuke, Tezuka Masahiro, Kanazawa Yuta, Katayanagi Satoshi, Nozawa Naohiro, Mizushima Takashi, Toyoda Shigeru, Fukuda Hirotsugu, Nakajima Toshiaki
Department of Cardiac and Vascular Surgery, Dokkyo Medical University School of Medicine, Shimotsuga, Japan.
Department of Pharmacology and Toxicology, Dokkyo Medical University School of Medicine, Shimotsuga, Tochigi, Japan.
Int J Cardiol Heart Vasc. 2022 Mar 18;39:101003. doi: 10.1016/j.ijcha.2022.101003. eCollection 2022 Apr.
Cardiovascular surgery in older patients with sarcopenia has high rates of major complications, long hospital stays, readmissions, and discharge transfers. However, the factors that influence the length of hospital stay are unknown. This study aimed was to identify the predictors of the prolonged hospital stay in patients with sarcopenia after cardiovascular surgery.
A total of 192 patients scheduled for cardiac surgery were enrolled in this retrospective observational study. Sarcopenia was diagnosed preoperatively. Clinical data from the preoperative, intraoperative, and perioperative periods were evaluated to determine the factors influencing the length of hospital stay.
The sarcopenia and non-sarcopenia groups differed significantly in age; body mass index; renal function; intubation time; transfusion of red blood cells; hospital transfer; and hemoglobin, brain natriuretic peptide, and albumin levels. Sarcopenia was the most significant factor influencing prolonged postoperative hospital stay, as well as prolonged intubation time. In the sarcopenia group, albumin levels and cardiopulmonary bypass time were the significant factors affecting hospital stay.
Sarcopenia was the most significant factor associated with prolonged postoperative hospital stay in patients who underwent cardiac surgery. In addition, improving sarcopenia, nutritional status, and shortening cardiopulmonary bypass time appear to shorten the hospital stay in patients with sarcopenia who underwent cardiovascular surgery.
患有肌肉减少症的老年患者进行心血管手术时，主要并发症发生率高、住院时间长、再入院率高且出院后需转院。然而，影响住院时间长短的因素尚不清楚。本研究旨在确定心血管手术后肌肉减少症患者住院时间延长的预测因素。
本回顾性观察性研究共纳入192例计划进行心脏手术的患者。术前诊断肌肉减少症。评估术前、术中和围手术期的临床数据，以确定影响住院时间长短的因素。
肌肉减少症组和非肌肉减少症组在年龄、体重指数、肾功能、插管时间、红细胞输注、转院以及血红蛋白、脑钠肽和白蛋白水平方面存在显著差异。肌肉减少症是影响术后住院时间延长以及插管时间延长的最显著因素。在肌肉减少症组中，白蛋白水平和体外循环时间是影响住院时间的重要因素。
肌肉减少症是心脏手术患者术后住院时间延长的最显著相关因素。此外，改善肌肉减少症、营养状况以及缩短体外循环时间似乎可以缩短接受心血管手术的肌肉减少症患者的住院时间。
