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膳食糖、超重和肥胖在 2 型糖尿病中的作用:叙述性评论。

The role of dietary sugars, overweight, and obesity in type 2 diabetes mellitus: a narrative review.

机构信息

Department Consumer Protection-Nutrition Policy-Sustainability Europe, Pfeifer & Langen GmbH & Co. KG, Cologne, Germany.

Knowledge Centre Sugar & Nutrition, Hilversum, The Netherlands.

出版信息

Eur J Clin Nutr. 2022 Nov;76(11):1497-1501. doi: 10.1038/s41430-022-01114-5. Epub 2022 Mar 21.

Abstract

Nowadays, there is still a popular belief that dietary sugars, in particular sucrose, are directly linked to the development of type 2 diabetes mellitus (T2DM). Furthermore, since insulin action is impaired in T2DM, it is still believed that excluding dietary sugars from the diet can adequately treat T2DM. This might be based on the assumption that dietary sugars have a stronger impact on blood glucose levels than other carbohydrates. Therefore, the aim of this review is to discuss the effects of dietary sugars intake, including sugar-sweetened beverages (SSBs) against the background of overall energy intake and weight gain in the development of T2DM. Furthermore, the effect of dietary sugars, including SSBs on glycemic control will be discussed. Results from various systematic reviews and meta-analyses do not support the idea that the intake of sucrose and other dietary sugars is linked to T2DM. Long-chain or complex carbohydrates can have a greater impact on postprandial glycemic response than sucrose. SSBs do not affect glycemic control if substituted for other calorie sources. Current scientific evidence clearly points toward excess energy intake followed by excess body fat gain being most relevant in the development of T2DM.

摘要

如今,仍有一种流行的观点认为,膳食糖,尤其是蔗糖,与 2 型糖尿病(T2DM)的发展直接相关。此外,由于 T2DM 患者的胰岛素作用受损,人们仍然认为从饮食中排除膳食糖可以充分治疗 T2DM。这可能基于这样的假设,即膳食糖对血糖水平的影响比其他碳水化合物更强。因此,本综述的目的是讨论在总能量摄入和体重增加的背景下,膳食糖(包括含糖饮料)的摄入对 T2DM 发展的影响。此外,还将讨论膳食糖(包括含糖饮料)对血糖控制的影响。各种系统评价和荟萃分析的结果并不支持摄入蔗糖和其他膳食糖与 T2DM 相关的观点。长链或复杂碳水化合物对餐后血糖反应的影响可能比蔗糖更大。如果用其他热量来源替代含糖饮料,不会影响血糖控制。目前的科学证据清楚地表明,在 T2DM 的发展过程中,过量的能量摄入继而导致过多的体脂增加是最重要的。

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