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侧卧位改良俯卧位超微经皮肾镜取石术治疗中等大小肾盂结石:一项随机临床试验。

Flank-Free Modified Supine Prone Ultra-Mini-Percutaneous Nephrolithotomy in Treatment of Medium-Sized Renal Pelvic Stone: A Randomized Clinical Trial.

机构信息

Faculty of Medicine, Department of Urology, Zagazig University, Sharkia, Egypt.

出版信息

J Endourol. 2022 Sep;36(9):1149-1154. doi: 10.1089/end.2022.0016. Epub 2022 Jul 26.

Abstract

Percutaneous nephrolithotomy (PCNL) is the standard treatment of renal stone >2 cm. Ultra-mini-percutaneous nephrolithotomy (UMP) had emerged in the past decade as a new technique in treating renal stones <2 cm. In this study we compared between the outcome of UMP in prone position with the outcome of UMP in modified flank free supine position (FFSP). A prospective randomized study was conducted between January 2016 and April 2020, including 122 patients, divided into two matched groups. Group A included 61 patients who underwent UMP in FFSP, and Group B included 61 patients who underwent UMP in a prone position. All patients had a single renal pelvic stone 1-2 cm. Patients with a single kidney, renal anomalies, body mass index ≥40 kg/m, history of ipsilateral renal surgery, and age <18 years were excluded. In both groups, the dilatation was done up to 13F; a holmium laser was used through a 9F ureteroscope for fragmentation. Nephrostomy tube and ureteral stent were used only when indicated. In total, 122 patients were divided into two groups. The mean age was 40.09 ± 13.63 and 39.67 ± 13.80 years in both groups, respectively. The operative time was 63.64 ± 9.22 and 78.48 ± 9.55 minutes in Groups A and B, respectively ( = 0.0001). The fluoroscopy time was 3.47 ± 0.56 and 4.45 ± 0.39 minutes in Groups A and B, respectively ( = 0.0001). No significant difference was shown between both groups regarding operative and postoperative complications. Shift to mini-PCNL was needed in one patient in Group A and four patients in Group B because of impaired vision. The hospital stay was 25.36 ± 4.23 and 26.13 ± 4.76 hours in both groups, respectively. The initial stone-free rate was 95.1% and 91.8% in both groups, respectively. UMP in modified supine position shows comparable results with UMP in the prone position regarding stone-free rate, hospital stay, and perioperative complication, with significantly shorter operative and fluoroscopy time.

摘要

经皮肾镜碎石术(PCNL)是治疗肾结石>2cm 的标准治疗方法。超微经皮肾镜碎石术(UMP)在过去十年中作为一种治疗肾结石<2cm 的新技术出现。本研究比较了俯卧位 UMP 与改良侧卧位自由仰卧位(FFSP)UMP 的结果。

一项前瞻性随机研究于 2016 年 1 月至 2020 年 4 月进行,共纳入 122 例患者,分为两组。A 组 61 例患者行 FFSP 下 UMP,B 组 61 例患者行俯卧位 UMP。所有患者均为单一肾盂结石 1-2cm。排除单侧肾脏、肾脏畸形、体重指数≥40kg/m、同侧肾脏手术史和年龄<18 岁的患者。两组均行 13F 扩张,9F 输尿管镜下钬激光碎石。仅在需要时使用肾造瘘管和输尿管支架。

共 122 例患者分为两组,两组平均年龄分别为 40.09±13.63 岁和 39.67±13.80 岁。A 组和 B 组的手术时间分别为 63.64±9.22 分钟和 78.48±9.55 分钟( = 0.0001)。A 组和 B 组的透视时间分别为 3.47±0.56 分钟和 4.45±0.39 分钟( = 0.0001)。两组患者在手术和术后并发症方面无显著差异。A 组 1 例患者和 B 组 4 例患者因视力受损转为迷你 PCNL。A 组和 B 组的住院时间分别为 25.36±4.23 小时和 26.13±4.76 小时。两组患者的初始结石清除率分别为 95.1%和 91.8%。

改良仰卧位 UMP 在结石清除率、住院时间和围手术期并发症方面与俯卧位 UMP 结果相当,手术时间和透视时间明显缩短。

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