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炎症性肠病的肝胆表现:实用方法

Hepatobiliary manifestations in inflammatory bowel disease: A practical approach.

作者信息

Núñez F Paulina, Castro Fabiola, Mezzano Gabriel, Quera Rodrigo, Diaz Diego, Castro Lorena

机构信息

Universidad de los Andes,Inflammatory Bowel Disease Program, Digestive Disease Center, Santiago 7600976, RM, Chile.

Universidad de los Andes,Hepatology Program, Digestive Disease Center, Santiago 7600976, RM, Chile.

出版信息

World J Hepatol. 2022 Feb 27;14(2):319-337. doi: 10.4254/wjh.v14.i2.319.

Abstract

Inflammatory bowel diseases (IBD) are associated with various hepatobiliary disorders. They can occur at any moment in the course of the disease or associated with the treatment. The prevalence of liver dysfunction can reach up to 50% in different studies. Nonalcoholic fatty liver disease is considered the most common hepatobiliary complication in IBD, while primary sclerosing cholangitis is the most specific. Management of hepatic manifestations in IBD involves a multidisciplinary approach that includes a high index of suspicion and joint management with hepatologists. The medical confrontation with abnormal liver tests must include an exhaustive study to determine if these patterns can be related to IBD, associated diseases or to the therapies used.

摘要

炎症性肠病(IBD)与多种肝胆疾病相关。它们可在疾病过程中的任何时候发生,或与治疗相关。在不同研究中,肝功能障碍的患病率可达50%。非酒精性脂肪性肝病被认为是IBD中最常见的肝胆并发症,而原发性硬化性胆管炎则是最具特异性的。IBD肝脏表现的管理需要多学科方法,包括高度的怀疑指数以及与肝病专家的联合管理。针对肝脏检查异常的医学应对必须包括详尽的研究,以确定这些模式是否与IBD、相关疾病或所用治疗方法有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/395d/8891676/858d02d93820/WJH-14-319-g001.jpg

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