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一项评估急性非复杂性憩室炎后常规结肠镜检查的作用及结直肠癌诊断发生率的多中心研究。

A multicentre study assessing the role of routine colonoscopy after acute uncomplicated diverticulitis and the incidence of colorectal cancer diagnosis.

作者信息

Singh Kaushiki, Liptrot Sarah, Tou Sam, Mehigan Brian, McCormick Paul, Ravi Narayasamy, Reynolds John, Al Chalabi Hasan

机构信息

Princess Royal University Hospital, King's College Hospital NHS Foundation Trust, London, UK.

University Hospitals of Derby & Burton NHS Foundation Trust, Derby, UK.

出版信息

Int J Colorectal Dis. 2023 Mar 28;38(1):84. doi: 10.1007/s00384-023-04374-0.

Abstract

PURPOSE

The low rates of colonic malignancy detected on interval colonoscopy for patients diagnosed with diverticulitis have led recent studies to question the utility of the practice. The aim of this study was to assess the detection rate of colorectal cancer on colonoscopy for patients with a first episode of acute uncomplicated diverticulitis across three separate centres in Ireland and the UK.

METHODS

A retrospective review was performed of patients with a first episode of acute, uncomplicated diverticulitis who underwent interval colonoscopy at three separate centres in the UK and Ireland between 2007 and 2019. The follow-up period was one year.

RESULTS

A total of 5485 patients were admitted with acute diverticulitis between the three centres. All patients had CT verified diverticulitis. A 90.8% (n = 4982) underwent subsequent colonic evaluation with colonoscopy. Of these, a histologically proven diagnosis of colorectal carcinoma was made in 1.28% (n = 64).

CONCLUSION

Routine colonoscopy following an episode of acute, uncomplicated diverticulitis may not be necessary in every patient. It may be appropriate to reserve this more invasive investigation for those with higher risk factors for malignancy.

摘要

目的

对于诊断为憩室炎的患者,在间隔期结肠镜检查中发现的结肠恶性肿瘤发生率较低,这使得近期的研究对这种做法的实用性提出了质疑。本研究的目的是评估在爱尔兰和英国三个不同中心,首次发作急性非复杂性憩室炎的患者在结肠镜检查中结直肠癌的检出率。

方法

对2007年至2019年期间在英国和爱尔兰三个不同中心接受间隔期结肠镜检查的首次发作急性非复杂性憩室炎患者进行回顾性研究。随访期为一年。

结果

三个中心共有5485例患者因急性憩室炎入院。所有患者的憩室炎均经CT证实。其中90.8%(n = 4982)随后接受了结肠镜检查进行结肠评估。在这些患者中,经组织学证实诊断为结直肠癌的有1.28%(n = 64)。

结论

首次发作急性非复杂性憩室炎后,并非每个患者都需要进行常规结肠镜检查。对于那些有较高恶性肿瘤风险因素的患者,保留这种侵入性更强的检查可能是合适的。

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