Department of Radiology, MINAR Cancer Hospital, Multan, Pakistan.
J Pak Med Assoc. 2022 Mar;72(3):560-563. doi: 10.47391/JPMA.2055.
Pyrexia of unknown origin (PUO) is a challenging entity in medical practice from a diagnostic point of view. Sub-Acute Thyroiditis (SAT), that is an inflammatory condition of thyroid, self-limiting and easily treatable, is a very rare cause for PUO with a few published cases and unfortunately not considered in routine for the differential diagnosis (DD) of PUO. Usually, it presents with mild thyrotoxicosis signs and symptoms, painful goiter, and rarely with cervical Lymph adenopathy. Thyroid antibodies might be negative, but inflammatory markers are usually raised. Anti-inflammatory drugs (NSAID) and steroids are a simple but very effective treatment. We present our experience for diagnosing and treating a female patient presenting with PUO. She was diagnosed as a case of sub-acute Thyroiditis on nuclear thyroid scan, High resolution ultrasound (HR-USG) of Thyroid and radioimmunoassay (RIA) for thyroid hormones and thyroid antibodies. The Patient was successfully treated with NSAIDs and steroids. The consent of the patient was taken to publish her case.
不明原因发热（PUO）是医学实践中从诊断角度来看具有挑战性的实体。亚急性甲状腺炎（SAT）是一种甲状腺炎症性疾病，具有自限性且易于治疗，但却是 PUO 的一种非常罕见的原因，仅有少数已发表的病例，并且在常规的 PUO 鉴别诊断（DD）中通常不考虑。通常，它表现为轻度甲状腺毒症的体征和症状、疼痛性甲状腺肿，并且很少伴有颈部淋巴结病。甲状腺自身抗体可能为阴性，但炎症标志物通常升高。非甾体抗炎药（NSAID）和类固醇是一种简单但非常有效的治疗方法。我们介绍了我们诊断和治疗一名出现 PUO 的女性患者的经验。她的核甲状腺扫描、甲状腺高分辨率超声（HR-USG）和甲状腺激素及甲状腺自身抗体的放射免疫分析（RIA）诊断为亚急性甲状腺炎。该患者成功接受 NSAID 和类固醇治疗。已征得患者同意发表其病例。
