探讨应用增强锥形束 CT 技术诊断垂直根折。
Exploring the use of enhanced cone-beam CT technique to diagnose vertical root fracture.
机构信息
Department of Dentomaxillofacial Radiology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Department of Endodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
出版信息
J Mech Behav Biomed Mater. 2022 Jun;130:105175. doi: 10.1016/j.jmbbm.2022.105175. Epub 2022 Mar 18.
OBJECTIVES
To explore the feasibility of using sodium iodide (NaI)+dimethyl sulfoxide (DMSO)+ethyl alcohol+ethyl acetate as a cone-beam CT (CBCT) contrast agent in the diagnosis of vertical root fracture (VRF).
METHODS
21 endodontically treated VRF teeth of 21 patients were collected in this study. All these 21 teeth were confirmed subtle fracture lines under transillumination, the number and position of fracture lines were recorded. All these patients had CBCT routine scanning (RS1) before extraction. After extraction, the teeth was performed micro-CT scanning and 3 in vitro CBCT scanning: CBCT routine scanning in vitro(RS2), CBCT enhanced scanning using meglumine diatrizoate (MD) as contrast agent(ES1); and CBCT enhanced scanning using NaI+DMSO+ethyl alcohol+ethyl acetate as contrast agent(ES2). The number of fracture lines was evaluated on all the 5 scanning modes and the accuracy of diagnosis was calculated.
RESULTS
In all, there were 43 fracture lines on the 21 teeth. The accuracy of detection of fracture lines of CBCT RS1, RS2, ES1, ES2 and micro-CT was 0%, 20.9% (9/43), 11.6% (5/43), 93% (40/43) and 95.3% (41/43) respectively. Significant differences were found between ES2 vs. RS2, ES2 vs. ES1 (p < 0.01); however, no significant difference was found between ES2 vs. micro-CT (p > 0.05).
CONCLUSION
CBCT enhanced scanning using NaI+DMSO+ethyl alcohol+ethyl acetate as contrast agent could be a prospective technique in the diagnosis of VRF.
目的
探索使用碘化钠（NaI）+二甲亚砜（DMSO）+乙醇+乙酸乙酯作为锥形束 CT（CBCT）对比剂诊断垂直根折（VRF）的可行性。
方法
本研究纳入 21 名患者的 21 颗根管治疗后 VRF 牙。所有这些牙齿在透照下均证实有细微的骨折线，记录骨折线的数量和位置。所有患者在拔牙前均进行 CBCT 常规扫描（RS1）。拔牙后，对牙齿进行 micro-CT 扫描和 3 种体外 CBCT 扫描：体外 CBCT 常规扫描（RS2）、使用泛影葡胺（MD）作为对比剂的 CBCT 增强扫描（ES1）；以及使用 NaI+DMSO+乙醇+乙酸乙酯作为对比剂的 CBCT 增强扫描（ES2）。在所有 5 种扫描模式下评估骨折线的数量，并计算诊断的准确性。
结果
总共 21 颗牙齿上有 43 条骨折线。CBCT RS1、RS2、ES1、ES2 和 micro-CT 检测骨折线的准确性分别为 0%（0/43）、20.9%（9/43）、11.6%（5/43）、93%（40/43）和 95.3%（41/43）。ES2 与 RS2、ES2 与 ES1 之间差异有统计学意义（p<0.01）；然而，ES2 与 micro-CT 之间差异无统计学意义（p>0.05）。
结论
使用 NaI+DMSO+乙醇+乙酸乙酯作为对比剂的 CBCT 增强扫描可能是诊断 VRF 的一种有前途的技术。
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