Department of Dentomaxillofacial Radiology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Department of Stomatology, Third People's Hospital of Danyang City, Danyang, China.
Dentomaxillofac Radiol. 2021 Oct 1;50(7):20210003. doi: 10.1259/dmfr.20210003. Epub 2021 Apr 20.
To evaluate the diagnostic accuracy using sodium iodide (NaI) and dimethyl sulfoxide (DMSO) as contrast agent in cone beam computed tomography (CBCT) scanning, and compare this with micro-CT.
18 teeth were cracked artificially by soaking them cyclically in liquid nitrogen and hot water. After pre-treatment with artificial saliva, the teeth were scanned in four modes: CBCT routine scanning without contrast agent (RS); CBCT with meglumine diatrizoate (MD) as contrast agent (ES1); CBCT with NaI + DMSO as contrast agent (ES2); and micro-CT (mCT). The number of crack lines was evaluated in all four modes. Depth of crack lines and number of cracks presented from the occlusal surface to the pulp cavity (Np) in ES2 and micro-CT images were evaluated.
There were 63 crack lines in all 18 teeth. 45 crack lines were visible on ES2 images as against four on the RS and ES1 images (0.05) and 37 on micro-CT images (0.05). Further, 34 crack lines could be observed on both ES2 and micro-CT images, and the average depth presented on ES2 images was 4.56 ± 0.88 mm and 3.89 ± 1.08 mm on micro-CT images (0.05). More crack lines could be detected from the occlusal surface to the pulp cavity on ES2 images than on micro-CT images (22 11).
CBCT with NaI +DMSO as the contrast agent was equivalent to micro-CT for number of crack lines and better for depth of crack lines. NaI + DMSO could be a potential CBCT contrast agent to improve diagnostic accuracy for cracked tooth.
评估使用碘酸钠(NaI)和二甲基亚砜(DMSO)作为对比剂在锥形束计算机断层扫描(CBCT)扫描中的诊断准确性,并与微 CT 进行比较。
将 18 颗牙齿通过在液氮和热水中循环浸泡人工开裂。用人工唾液预处理后,牙齿以 4 种模式进行扫描:无对比剂的 CBCT 常规扫描(RS);用泛影葡胺(MD)作为对比剂的 CBCT(ES1);用 NaI+DMSO 作为对比剂的 CBCT(ES2);和微 CT(mCT)。在所有 4 种模式下评估裂线数量。评估 ES2 和微 CT 图像中从咬合面到牙髓腔的裂线深度和裂线数量(Np)。
所有 18 颗牙齿共有 63 条裂线。ES2 图像上可见 45 条裂线,而 RS 和 ES1 图像上分别可见 4 条和 37 条(0.05),微 CT 图像上可见 37 条(0.05)。此外,ES2 和微 CT 图像上均可观察到 34 条裂线,ES2 图像上的平均裂线深度为 4.56±0.88mm,微 CT 图像上为 3.89±1.08mm(0.05)。ES2 图像上从咬合面到牙髓腔可检测到更多的裂线,比微 CT 图像上多 22 条(11)。
NaI+DMSO 作为对比剂的 CBCT 在裂线数量上与微 CT 相当,在裂线深度上优于微 CT。NaI+DMSO 可能是一种潜在的 CBCT 对比剂,可提高对裂牙的诊断准确性。