Triarico Silvia, Rinninella Emanuele, Attinà Giorgio, Romano Alberto, Maurizi Palma, Mastrangelo Stefano, Ruggiero Antonio
Pediatric Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
UOC of Clinical Nutrition, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Front Biosci (Elite Ed). 2022 Feb 8;14(1):4. doi: 10.31083/j.fbe1401004.
Nutritional status plays a vital role in the growth of children. In pediatric patients, disease-related malnutrition is a dynamic and multifactorial process supported by several factors such as inflammation, increased energy expenditure, decreased intake or reduced utilization of nutrients. In pediatric patients with malignancies, sarcopenia may coexist with malnutrition, amplifying its negative impact on prognosis. Careful monitoring of nutritional status both at diagnosis and during chemotherapy treatment allows early detection of the risk and/or presence of malnutrition. A rapid and personalized nutritional intervention can improve adherence to treatment, reduce complications and improve the patients' quality of life.
营养状况在儿童生长发育中起着至关重要的作用。在儿科患者中，疾病相关的营养不良是一个动态的多因素过程，受多种因素支持，如炎症、能量消耗增加、营养摄入减少或营养利用降低。在患有恶性肿瘤的儿科患者中，肌肉减少症可能与营养不良同时存在，加剧其对预后的负面影响。在诊断时和化疗治疗期间仔细监测营养状况，有助于早期发现营养不良的风险和/或存在情况。快速且个性化的营养干预可以提高治疗依从性、减少并发症并改善患者的生活质量。
