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微创经皮肾镜取石术后并发急性肺栓塞和严重溶栓后肾出血:罕见病例报告。

Acute pulmonary embolism and severe post thrombolysis renal bleeding, two deadly complications following mini-percutaneous nephrolithotomy: a rare case report.

机构信息

Department of Urology, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, #59 Liuting Street, Ningbo City, 315010, Zhejiang Province, China.

School of Medicine, Ningbo University, No.818 Fenghua Road, Ningbo City, 315000, Zhejiang Province, China.

出版信息

BMC Surg. 2022 Mar 23;22(1):108. doi: 10.1186/s12893-022-01561-8.

DOI:10.1186/s12893-022-01561-8
PMID:35321709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8944081/
Abstract

BACKGROUND

Acute pulmonary embolism and severe renal bleeding are two lethal postoperative complications, but there has been no report that involves both of them after mini-percutaneous nephrolithotomy.

CASE PRESENTATION

A 62-year-old woman was admitted to our hospital with extremely severe hydronephrosis and multiple right renal calculi. After thorough examination, she received prone-position mini-percutaneous nephrolithotomy under spinal anaesthesia. Three days postoperatively, the patient complained of chest pain and dyspnea. Computed tomography pulmonary angiogram (CTPA) showed multiple embolisms in the left pulmonary artery and its branches. Symptoms were relieved after anticoagulant and thrombolysis therapy. On the 6th postoperative day, the patient developed shortness of breath, computed tomography angiography (CTA) showed massive hemorrhage in the right kidney, diffused contrast medium in the middle and lower part of the right kidney was seen during digital substraction angiography (DSA). Superselective right renal artery embolization (SRAE) was then applied using coil to occlude the responsible artery. The patient generally recovered under conscientious care and was approved to be discharged 26 days postoperatively.

CONCLUSIONS

This is the first case that involved both acute pulmonary embolism and severe post thrombolysis renal bleeding. The importance of D-dimer in the prediction and early detection of pulmonary embolism should be noted. For post thrombolysis renal bleeding, SRAE is considered as a reliable treatment.

摘要

背景

急性肺栓塞和严重肾出血是两种致命的术后并发症,但尚未有经皮肾镜碎石术后同时发生这两种并发症的报道。

病例介绍

一名 62 岁女性因重度肾积水和多发右肾结石入院。经全面检查后,患者在椎管内麻醉下行俯卧位微创经皮肾镜碎石术。术后 3 天,患者诉胸痛、呼吸困难。肺部计算机断层血管造影(CTPA)显示左肺动脉及其分支多发栓塞。经抗凝溶栓治疗后症状缓解。术后第 6 天,患者出现呼吸急促,CT 血管造影(CTA)显示右肾大量出血,数字减影血管造影(DSA)见右肾中下部弥散性造影剂。随后采用弹簧圈行超选择性右肾动脉栓塞术(SRAE)闭塞责任动脉。经精心护理,患者一般情况恢复良好,术后 26 天获准出院。

结论

这是首例同时发生急性肺栓塞和溶栓后严重肾出血的病例。应注意 D-二聚体在预测和早期发现肺栓塞中的重要性。对于溶栓后肾出血,SRAE 被认为是一种可靠的治疗方法。

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本文引用的文献

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Superselective Renal Artery Embolization Management of Post-percutaneous Nephrolithotomy Hemorrhage and Its Methods.经皮肾镜取石术后出血的超选择性肾动脉栓塞治疗及其方法
Front Surg. 2020 Nov 26;7:582261. doi: 10.3389/fsurg.2020.582261. eCollection 2020.
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The efficacy and safety of miniaturized percutaneous nephrolithotomy versus standard percutaneous nephrolithotomy: A systematic review and meta-analysis of randomized controlled trials.微型经皮肾镜碎石术与标准经皮肾镜碎石术的疗效和安全性:系统评价和随机对照试验的荟萃分析。
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