肺移植联合心脏修复治疗双侧肺动脉发育不良伴动脉导管未闭。
Lung transplantation with concomitant cardiac repair for congenital hypoplasia of bilateral pulmonary arteries and patent ductus arteriosus.
机构信息
Department of Surgery, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan.
Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
出版信息
J Cardiothorac Surg. 2022 Mar 23;17(1):49. doi: 10.1186/s13019-022-01792-z.
BACKGROUND
Profound pulmonary arterial hypertension with end-stage right heart failure is considered to be the main cause of death in children with un-repaired congenital heart disease, and the traditional surgical treatment is heart-lung transplantation. We performed bilateral lung transplantation (LTx) with concomitant cardiac repair, and the patient has uplifting outcome.
CASE PRESENTATION
We have reported the case of a patient with congenital hypoplasia of the bilateral pulmonary arteries and patent ductus arteriosus. The patient's clinical condition was gradually worsening and severely limited his ability to perform the activities of daily life. Bilateral LTx with concomitant patent ductus arteriosus repair was performed at the age of 11 years. The postoperative course was smooth and cardiopulmonary function nearly returned to normal according to radiological and laboratory examinations.
CONCLUSIONS
Bilateral LTx with concomitant cardiac repair may be superior to heart-lung transplantation in the case of the specific congenital heart disease.
背景
伴有终末期右心衰竭的严重肺动脉高压被认为是未修复先天性心脏病儿童死亡的主要原因，传统的手术治疗是心肺移植。我们对该患者实施了双侧肺移植（LTx）联合心脏修复术，患者的预后得到改善。
病例介绍
我们报告了一例双侧肺动脉发育不良伴动脉导管未闭的患者。患者的临床状况逐渐恶化，严重限制了其日常生活活动能力。该患者在 11 岁时接受了双侧 LTx 联合动脉导管未闭修补术。术后过程顺利，心肺功能根据影像学和实验室检查几乎恢复正常。
结论
在特定的先天性心脏病病例中，双侧 LTx 联合心脏修复术可能优于心肺移植。
Zotero 插件