关于 Arieh Berger 和 K. Linderstrøm-Lang 的“水溶液中聚-dl-丙氨酸的氘交换”一文。
On 'Deuterium exchange of poly-dl-alanine in aqueous solution' by Arieh Berger and K. Linderstrøm-Lang.
机构信息
Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15208, USA.
出版信息
Arch Biochem Biophys. 2022 Sep 15;726:109185. doi: 10.1016/j.abb.2022.109185. Epub 2022 Mar 20.
PMID:35321824
Abstract
This commentary highlights the landmark manuscript published in 1957 by Arieh Berger and K. Linderstrøm-Lang that describes the measurement and analysis of hydrogen exchange rates. This highly referenced manuscript is recognized because the impact hydrogen exchange has had on characterizing the structure and dynamics of natively folded proteins and folding intermediates.
摘要
这篇评论重点介绍了 Arieh Berger 和 K. Linderstrøm-Lang 于 1957 年发表的具有里程碑意义的手稿，该手稿描述了氢交换率的测量和分析。这篇被高度引用的手稿之所以得到认可，是因为氢交换在描述天然折叠蛋白质和折叠中间体的结构和动力学方面产生了巨大影响。
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