Department of Anesthesiology and Perioperative Medicine, Oregon Health and Science University, Portland, OR.
Biostatistics and Design Program, Oregon Health and Science University, Portland, OR.
Pain Physician. 2022 Mar;25(2):E365-E374.
Piriformis syndrome is a constellation of symptoms associated with low back, gluteal, and sciatic pain. One treatment for piriformis syndrome is the injection of local anesthetic, steroid, or botulinum toxin into the piriformis muscle. Various approaches for needle navigation into the piriformis muscle have been described using fluoroscopy or ultrasound. This study introduces a new method of image guidance combining fluoroscopy and ultrasound.
The primary aim of this study was examining whether the imaging modality used for needle guidance was associated with significant differences in pre- and post-piriformis injection pain scores. Secondary objectives were assessing differences in adverse events and procedure time.
This study is a retrospective cohort study.
This study was conducted at Oregon Health and Science University's Comprehensive Pain Center, Portland, OR, USA.
Institutional chart review was performed from 09/21/2014 to 01/21/2020 to identify patients that underwent piriformis steroid injections which generated a list of 95 patients and totaled 154 procedures. Inclusion criteria were met for 78 patients and 109 procedures. Pain scores were modeled longitudinally using robust variance estimates. The nonparametric Kruskal-Wallis test was used for procedure duration, while adverse events were too rare to evaluate statistically.
Piriformis steroid injections using the combined ultrasound and fluoroscopy technique had the lowest mean post-procedure pain score of 1.3 (SD 1.7) and the largest change in pain with a score difference of -3.9 (SD 2.1). Procedure durations were 8 (quartiles 5 to 10), 10 (quartiles 7 to 13), and 11 minutes (quartiles 9 to 13) for fluoroscopy alone, ultrasound alone, and combined techniques, respectively. All 3 modalities had duration ranges of minimum time of 3-5 minutes and a maximum time of 25-28 minutes. Adverse events across all imaging strategies were noted in 5 patients at the time of procedure and in 7 patients during follow-up appointments, the most common symptom being transient leg weakness or numbness.
The major limitation is the retrospective collection of data. Another limitation is that 6 different providers performed the injections, which may influence procedural consistency. Additionally, the inclusion of subjects with low pre-procedure pain scores could create a floor effect that minimized the occurrence of clinically significant shifts in pain scores. Adverse events were too few across all groups to assess.
Piriformis injections using combined fluoroscopic and ultrasound guidance provides comparable efficiency to standard techniques and may result in improved accuracy into the target and thus improved efficacy. Larger prospective trials are required to comprehensively examine the efficacy of this novel technique.
梨状肌综合征是一种与下腰痛、臀肌和坐骨神经痛相关的症状组合。梨状肌综合征的一种治疗方法是将局部麻醉剂、类固醇或肉毒杆菌毒素注射到梨状肌中。已经描述了使用透视或超声导航将针导航到梨状肌中的各种方法。本研究介绍了一种结合透视和超声的新图像引导方法。
本研究的主要目的是检查用于针引导的成像方式是否与梨状肌注射前后疼痛评分的显著差异相关。次要目标是评估不良事件和程序时间的差异。
这是一项回顾性队列研究。
本研究在美国俄勒冈健康与科学大学综合疼痛中心进行,波特兰,OR。
对 2014 年 9 月 21 日至 2020 年 1 月 21 日的机构图表进行审查,以确定接受梨状肌类固醇注射的患者,生成了 95 名患者的名单,共进行了 154 次手术。符合纳入标准的有 78 名患者和 109 例。使用稳健方差估计对疼痛评分进行纵向建模。非参数 Kruskal-Wallis 检验用于程序持续时间,而不良事件太罕见,无法进行统计评估。
使用联合超声和透视技术的梨状肌类固醇注射术后疼痛评分最低,平均为 1.3(标准差 1.7),疼痛评分变化最大,为-3.9(标准差 2.1)。透视单独使用的程序持续时间分别为 8 分钟(四分位数 5 至 10)、10 分钟(四分位数 7 至 13)和 11 分钟(四分位数 9 至 13),超声单独使用和联合技术的程序持续时间分别为 8 分钟(四分位数 5 至 10)、10 分钟(四分位数 7 至 13)和 11 分钟(四分位数 9 至 13)。所有 3 种模式的持续时间范围最小为 3-5 分钟,最大为 25-28 分钟。在所有成像策略中,有 5 名患者在手术时和 7 名患者在随访期间出现了不良事件,最常见的症状是短暂的腿部无力或麻木。
主要限制是回顾性收集数据。另一个限制是,有 6 位不同的医生进行了注射,这可能会影响程序的一致性。此外,纳入的低术前疼痛评分患者可能会产生地板效应,从而最小化疼痛评分的临床显著变化。所有组的不良事件都太少,无法进行评估。
使用联合透视和超声引导的梨状肌注射与标准技术具有相当的效率,并且可能导致目标的准确性提高,从而提高疗效。需要更大规模的前瞻性试验来全面检查这种新技术的疗效。