McHugh T P, Robson M C, Heggers J P, Phillips L G, Smith D J, McCollum M C
Surgery. 1986 Oct;100(4):661-4.
Cadaver allograft skin, porcine xenograft skin, and amniotic membranes have been proved to be adequate temporary thermal wound coverings in four clinical situations: coverage of shallow wounds while awaiting epithelialization (SW), coverage of deep wounds after eschar excision (DEW), coverage of widely meshed autograft while awaiting closure of interstices (AC), and coverage of massive donor sites (DS). This study was undertaken to evaluate the therapeutic efficacy of a new biosynthetic bilaminate dressing, Biobrane. Two hundred one applications of Biobrane were studied in 82 SW, 46 DEW, 19 AC, 54 DS. A total of 124 applications were left in place until healing occurred, with a mean healing time of 12.8 days. Sixty of SW, 10/46 DEW, 10/19 AC, and 44/54 DS remained intact until complete healing. Only four DEW, two SW, and 0 AC applications had to be removed because of suppuration. Twenty five of the applications (SW and DEW) with the Biobrane glove had rare complications.
尸体同种异体皮肤、猪异种异体皮肤和羊膜已被证明在四种临床情况下是合适的临时热伤口覆盖物：在等待上皮化时覆盖浅伤口（SW）、焦痂切除后覆盖深伤口（DEW）、在等待间隙闭合时覆盖广泛网状自体移植物（AC）以及覆盖大面积供皮区（DS）。本研究旨在评估一种新型生物合成双层敷料Biobrane的治疗效果。在82例SW、46例DEW、19例AC、54例DS中对Biobrane进行了201次应用研究。共有124次应用保留至愈合，平均愈合时间为12.8天。60例SW、10/46例DEW、10/19例AC和44/54例DS在完全愈合前保持完整。只有4例DEW、2例SW和0例AC应用因化脓而不得不移除。使用Biobrane手套的25次应用（SW和DEW）有罕见并发症。
