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生物膜的应用经验:成功的使用方法及注意事项

Experience with biobrane: uses and caveats for success.

作者信息

Greenwood John E, Clausen Jill, Kavanagh Sheila

机构信息

Burns Unit, Royal Adelaide Hospital, North Terrace, Adelaide 5000, South Australia.

出版信息

Eplasty. 2009 Jun 26;9:e25.

PMID:19633707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2704145/
Abstract

OBJECTIVE

To present some of our experience with Biobrane (a total of 703 patients in 7 years) in a range of uses in burn practice and to illustrate the caveats that we have found applicable in maintaining our success with this versatile material.

METHODS

Retrospective analysis of theatre records, medical notes, and photography database to categorize our experience with Biobrane. Thorough assessment of our surgical and nursing protocols (both literature and experience influenced) to identify caveats for successful use.

RESULTS

Pivotal steps are revealed in wound selection, wound preparation, material application, dressing, and subsequent nursing care that have led to overwhelming success in definitive management of superficial partial thickness to middermal burns (ensuring pain relief, allowing early mobilization, tolerance of dressing changes and therapy, and earlier hospital discharge). Its many uses in a broad range of common burn situations are demonstrated and tips provided to achieve best outcome.

CONCLUSIONS

Biobrane is not a panacea but it is extremely versatile. The different potential uses have learning curves, and suggestions are provided to flatten these.

摘要

目的

介绍我们在7年中对703例患者使用生物膜的一些经验,这些经验涵盖了烧伤治疗中的一系列应用,并阐述我们发现在成功使用这种多功能材料时适用的注意事项。

方法

回顾性分析手术记录、病历和摄影数据库,以对我们使用生物膜的经验进行分类。全面评估我们受文献和经验影响的手术及护理方案,以确定成功使用的注意事项。

结果

在伤口选择、伤口处理、材料应用、包扎及后续护理中揭示了关键步骤,这些步骤在浅Ⅱ度至中厚皮烧伤的确定性治疗中取得了巨大成功(确保缓解疼痛、允许早期活动、耐受换药和治疗以及提前出院)。展示了其在广泛的常见烧伤情况中的多种用途,并提供了实现最佳效果的提示。

结论

生物膜并非万灵药,但它用途极为广泛。不同的潜在用途存在学习曲线,并提供了使这些曲线变平缓的建议。

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Experience with biobrane: uses and caveats for success.生物膜的应用经验:成功的使用方法及注意事项
Eplasty. 2009 Jun 26;9:e25.
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The search for an ideal temporary skin substitute: AWBAT.
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Management of partial thickness facial burns (comparison of topical antibiotics and bio-engineered skin substitutes).面部浅度烧伤的治疗(局部用抗生素与生物工程皮肤替代物的比较)
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使用Biobranetm对切向切除的浅度热烧伤进行确定性覆盖的早期经验。
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The use of a non-medicated dressing for superficial-partial thickness burns in children: a case series and review.非药物敷料用于儿童浅Ⅱ度烧伤:病例系列及综述
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Sprayable and biodegradable, intrinsically adhesive wound dressing with antimicrobial properties.具有抗菌特性的可喷雾、可生物降解的内源性粘性伤口敷料。
Bioeng Transl Med. 2019 Dec 13;5(1):e10149. doi: 10.1002/btm2.10149. eCollection 2020 Jan.
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Comparative effectiveness of Biobrane®, RECELL® Autologous skin Cell suspension and Silver dressings in partial thickness paediatric burns: BRACS randomised trial protocol.Biobrane®、RECELL® 自体皮肤细胞悬液和银敷料在小儿浅度烧伤中的比较效果:BRACS 随机试验方案
Burns Trauma. 2019 Oct 31;7:33. doi: 10.1186/s41038-019-0165-0. eCollection 2019.
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Regenerative Scar-Free Skin Wound Healing.再生无瘢痕皮肤创伤愈合。
Tissue Eng Part B Rev. 2019 Aug;25(4):294-311. doi: 10.1089/ten.TEB.2018.0350.
10
Biobrane™ versus acticoat™ for the treatment of mid-dermal pediatric burns: a prospective randomized controlled pilot study.生物膜™与活性银离子抗菌敷料™治疗小儿真皮中层烧伤的前瞻性随机对照试验研究
Int J Burns Trauma. 2018 Jun 20;8(3):63-67. eCollection 2018.
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Use of Biobrane for extensive posterior donor site wounds.生物膜用于广泛的供体部位后位伤口。
J Burn Care Rehabil. 1995 May-Jun;16(3 Pt 1):335-6. doi: 10.1097/00004630-199505000-00023.
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Use of Biobrane in management of scalds.生物膜在烫伤治疗中的应用。
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Use of Biobrane in wound management.
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Biosynthetic skin substitute versus frozen human cadaver allograft for temporary coverage of excised burn wounds.生物合成皮肤替代物与冷冻人类尸体同种异体移植物用于切除烧伤创面的临时覆盖
J Trauma. 1987 Feb;27(2):155-7. doi: 10.1097/00005373-198702000-00010.
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Therapeutic efficacy of Biobrane in partial- and full-thickness thermal injury.生物膜在部分厚度和全厚度热损伤中的治疗效果。
Surgery. 1986 Oct;100(4):661-4.
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Uses and abuses of a biosynthetic dressing for partial skin thickness burns.生物合成敷料在浅Ⅱ度烧伤治疗中的应用与滥用
Burns. 1989 Aug;15(4):254-6. doi: 10.1016/0305-4179(89)90044-2.