School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, China.
Research Center for Medical Artificial Intelligence, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
J Magn Reson Imaging. 2022 Oct;56(4):1055-1065. doi: 10.1002/jmri.28173. Epub 2022 Mar 24.
Multichannel tactile stimulation devices is need to investigate human finger population receptive field (pRF) characteristics in the primary somatosensory cortex during functional magnetic resonance imaging (fMRI).
To accurately characterize right-hand somatosensory representation based on the Bayesian pRF model.
Prospective.
A water phantom and six healthy participants (four males, mean 23.8 years old).
FIELD STRENGTH/SEQUENCE: T1-weighted magnetization-prepared rapid gradient-echo, T2*-weighted echo planar imaging at 3 T.
The piezoelectric actuated tactile stimulation device consisted of execution unit and control unit. The output performance of the device was measured by a laser displacement sensor. The effect of the device on images' signal-to-noise ratio (SNR) was measured by phantom experiments. The activation representation arrangement order, relative volumes, and receptive field size of the right hand were assessed during the along-digits and cross-digits paradigms.
The normality of the data was tested by the Shapiro-Wilk method. A paired-sample t test was performed to test pRF characteristics for all digit pairings. The significance level was set to P = 0.05 (false discovery rate [FDR] correct).
Percussive stimulation provided by the piezoelectric actuated tactile stimulator had a stable displacement (2.64 mm) over a wide range of vibration frequencies (0-30 Hz). The output delay of the device was 1 millisecond. The device did not affect the image's SNR (without the device: SNR = 138.24 ± 7.87, temporal SNR [TSNR] = 440.03 ± 52.08. With the device: SNR = 138.06 ± 8.44, TSNR = 438.52 ± 56.38. P = 0.88, P = 0.46). Representations of right-hand fingers showed the same arrangement order in both experiments (D1-D5 arranged along the central sulcus). However, the relative volumes of D3 showed significant differences in S1 (P = 0.003). Among four subareas, the relative volumes of D3 were significantly different in area 1 (P = 0.047).
This developed stimulator, through experimental verification, could play a role in pRF mapping exploration.
2 TECHNICAL EFFICACY STAGE: 1.
在功能磁共振成像（fMRI）期间，需要使用多通道触觉刺激设备来研究初级体感皮层中人类手指的群体感受野（pRF）特征。
基于贝叶斯 pRF 模型准确描述右手体感代表区。
前瞻性。
水模体和六名健康参与者（男性 4 名，平均 23.8 岁）。
磁场强度/序列：3T 下的 T1 加权磁化准备快速梯度回波，T2*-加权回波平面成像。
压电致动触觉刺激设备由执行单元和控制单元组成。通过激光位移传感器测量设备的输出性能。通过体模实验测量设备对图像信噪比（SNR）的影响。在沿指和交叉指范式期间，评估右手的激活表示排列顺序、相对体积和感受野大小。
通过 Shapiro-Wilk 方法检验数据的正态性。对所有数字对进行配对样本 t 检验，以检验 pRF 特征。显著性水平设置为 P=0.05（错误发现率[FDR]校正）。
压电致动触觉刺激器提供的敲击刺激在很宽的振动频率范围内（0-30Hz）具有稳定的位移（2.64mm）。设备的输出延迟为 1 毫秒。该设备不会影响图像的 SNR（无设备：SNR=138.24±7.87，时间 SNR[TSNR]=440.03±52.08。有设备：SNR=138.06±8.44，TSNR=438.52±56.38。P=0.88，P=0.46）。在两项实验中，右手手指的代表区都表现出相同的排列顺序（D1-D5 沿着中央沟排列）。然而，S1 中 D3 的相对体积存在显著差异（P=0.003）。在四个亚区中，D3 的相对体积在 1 区有显著差异（P=0.047）。
该开发的刺激器通过实验验证，可以在 pRF 映射探索中发挥作用。
2 技术功效阶段：1。
