Skopicheva V I, Skopichev V G, Sorokin A B
Tsitologiia. 1986 Jul;28(7):687-92.
A scanning electron microscope study of the Swiss 3T3 cell surface topography was made in association with changes in proliferative activity. On the phase of logarithmic growth the cell shape is similar to that of an actively migrating fibroblast. When the growth promoting factors are depleted, the cells are seen spread and forming numerous cell-to-cell contacts. The stimulation of cell proliferation induced by a 10% serum or by epidermal growth factor is associated with a disturbance of cell interaction because of the centripetal cell contraction.
结合增殖活性的变化，对瑞士3T3细胞表面形貌进行了扫描电子显微镜研究。在对数生长期，细胞形状类似于活跃迁移的成纤维细胞。当生长促进因子耗尽时，可见细胞铺展并形成大量细胞间接触。10%血清或表皮生长因子诱导的细胞增殖刺激与细胞向心收缩导致的细胞相互作用紊乱有关。
