[Prospective randomized study of the efficacy of adjuvant hormone therapy in patients with breast cancer].

Tentative results of a randomized controlled evaluation of the effectiveness of adjuvant hormonal therapy of breast cancer are discussed. The data on 118 cases examined in 1981-1984 were considered on the basis of menstrual cycle characteristics and extension of tumor. The results obtained as a result of an average 16.9 month-long examination pointed to a relatively higher recurrence incidence in untreated patients and suggested that such studies should be continued. Tolerance evaluation established a higher incidence of side-effects in cases treated with diethylstilbestrol (33.3%) than with tamoxifen (3.8%).