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[用免疫酶法检测人血清中的狂犬病病毒抗体]

[Detection of rabies virus antibodies in human blood serum by an immunoenzyme method].

作者信息

Botvinkin A D, Selimov M A, Zgurskaia G N, Kulikov L G, Aksenova T A

出版信息

Vopr Virusol. 1986 May-Jun;31(3):333-4.

PMID:3532544
Abstract

In a coded experiment on rabies virus antibody detection in the blood sera of humans immunized with rabies vaccines, coincidence of the results of indirect ELISA, neutralization test and radial hemolysis test (RHT) was observed in 83% and 90% of the cases. The correlation coefficient of antibody titres in ELISA and NT was r = +0.75, ELISA and RHT r = +0.81. Instances of discrepancy of the results were observed with sera of low titres, no more than 1:50 by neutralization test.

摘要

在一项关于用狂犬病疫苗免疫的人血清中狂犬病病毒抗体检测的编码实验中,间接酶联免疫吸附测定(ELISA)、中和试验和放射状溶血试验(RHT)结果的符合率在83%和90%的病例中被观察到。ELISA和中和试验中抗体滴度的相关系数为r = +0.75,ELISA和RHT为r = +0.81。在中和试验滴度不超过1:50的低滴度血清中观察到结果不一致的情况。

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