Baker C C
Yale J Biol Med. 1986 Jul-Aug;59(4):387-93.
Sepsis is responsible for 75 percent of late deaths following major thermal injury or traumatic injury. Efforts to prevent and/or control sepsis should include an understanding of normal host resistance, proper resuscitation techniques, and nutritional support. Recent studies identifying T suppressor cell abnormalities in burn patients and macrophage defects in trauma patients are presented in this paper. Concluding remarks regarding future directions for research and therapy in this area are also made.
脓毒症是导致严重热烧伤或创伤后75%晚期死亡的原因。预防和/或控制脓毒症的努力应包括了解正常宿主抵抗力、适当的复苏技术和营养支持。本文介绍了近期关于烧伤患者T抑制细胞异常和创伤患者巨噬细胞缺陷的研究。文中还对该领域未来的研究和治疗方向作了总结性评论。