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创伤患者的免疫机制与宿主抵抗力

Immune mechanisms and host resistance in the trauma patient.

作者信息

Baker C C

出版信息

Yale J Biol Med. 1986 Jul-Aug;59(4):387-93.

Abstract

Sepsis is responsible for 75 percent of late deaths following major thermal injury or traumatic injury. Efforts to prevent and/or control sepsis should include an understanding of normal host resistance, proper resuscitation techniques, and nutritional support. Recent studies identifying T suppressor cell abnormalities in burn patients and macrophage defects in trauma patients are presented in this paper. Concluding remarks regarding future directions for research and therapy in this area are also made.

摘要

脓毒症是导致严重热烧伤或创伤后75%晚期死亡的原因。预防和/或控制脓毒症的努力应包括了解正常宿主抵抗力、适当的复苏技术和营养支持。本文介绍了近期关于烧伤患者T抑制细胞异常和创伤患者巨噬细胞缺陷的研究。文中还对该领域未来的研究和治疗方向作了总结性评论。

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本文引用的文献

1
Epidemiology of trauma deaths.创伤死亡的流行病学
Am J Surg. 1980 Jul;140(1):144-50. doi: 10.1016/0002-9610(80)90431-6.
2
The immune consequences of trauma.创伤的免疫后果。
Surg Clin North Am. 1982 Feb;62(1):167-81. doi: 10.1016/s0039-6109(16)42643-5.
7
Host factors in bacteremia.
Am J Med. 1983 Jul 28;75(1B):19-25. doi: 10.1016/0002-9343(83)90068-2.
9
The current status of burn research.
J Trauma. 1974 Jan;14(1):1-8.
10
Postsplenectomy sepsis.脾切除术后脓毒症
Perspect Pediatr Pathol. 1973;1:285-311.

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