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从灾难遇难者身份识别的角度来看,快速 DNA 检测是否是一个重大变革?

Rapid DNA from a disaster victim identification perspective: Is it a game changer?

机构信息

Victorian Institute of Forensic Medicine, Victoria, Australia; Department of Forensic Medicine, Monash University, Victoria, Australia.

Office of the Chief Forensic Scientist, Victoria Police Forensic Services Department, Victoria, Australia.

出版信息

Forensic Sci Int Genet. 2022 May;58:102684. doi: 10.1016/j.fsigen.2022.102684. Epub 2022 Mar 7.

Abstract

As an emerging technology, Rapid DNA has demonstrated its utility for law enforcement in the provision of DNA profiling data at the point of arrest, often not requiring analyst review of the profiles generated. Recently, efforts have centred on the evaluation of Rapid DNA (without analyst review) and modified Rapid DNA (requiring review by a trained analyst) for application to crime scene samples. In a broader forensic context, however, another application for Rapid DNA is its use to process post-mortem samples to assist with the identification of deceased persons; and while gaps in our knowledge remain as to how Rapid DNA instruments perform with these sample types (often compromised with regards to their yield and quality of DNA), they have been successfully deployed in the field to assist in the identification of disaster victims (as exemplified during the 2018 Californian wildfire). This review aims to provide the current research landscape for the forensic application of Rapid DNA as an emerging technology from a Disaster Victim Identification perspective.

摘要

作为一项新兴技术,Rapid DNA 在提供逮捕时的 DNA 特征数据方面已经证明了其在执法中的实用性,通常不需要分析师对生成的特征进行审查。最近,人们的注意力集中在评估 Rapid DNA(无需分析师审查)和改良的 Rapid DNA(需要经过受过培训的分析师审查)在犯罪现场样本中的应用。然而,在更广泛的法医背景下,Rapid DNA 的另一个应用是用于处理死后样本以协助识别死者;尽管我们对 Rapid DNA 仪器如何处理这些样本类型的性能(通常在产量和 DNA 质量方面受到影响)知之甚少,但它们已成功应用于现场以协助识别灾难受害者(如 2018 年加利福尼亚野火期间的例子)。本综述旨在从灾难受害者识别的角度提供 Rapid DNA 作为新兴技术在法医应用中的最新研究现状。

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