Low J A, Galbraith R S, Sauerbrei E E, Muir D W, Killen H L, Pater E, Karchmar E J
Am J Obstet Gynecol. 1986 Oct;155(4):750-6. doi: 10.1016/s0002-9378(86)80013-8.
Two hundred twenty-six moderate- or high-risk newborn infants were studied to examine the relationship between ultrasound findings in the newborn period and at 6 months and motor and cognitive deficits at 1 year. A three-part classification of abnormal ultrasound findings was used to grade intraventricular hemorrhage, ventriculomegaly, and parenchymal lesions. Abnormal ultrasound findings were observed in 48 infants, of whom 21 had intraventricular hemorrhage, 18 persistent ventriculomegaly, and nine parenchymal lesions. The incidence of deficits was as follows: normal ultrasound examination, 20%; intraventricular hemorrhage, 33%; persistent ventriculomegaly, 67%; and parenchymal lesions, 89%. The present study indicates that serial ultrasound examinations are indicated in preterm newborn infants less than 1500 gm and in selected newborn infants at risk and greater than 1500 gm at birth. The three-part classification of abnormal ultrasound findings should be used because of the predictive significance of persistent ventriculomegaly and parenchymal lesions for motor and cognitive deficits at 1 year of age.
对226名中度或高危新生儿进行了研究，以探讨新生儿期及6个月时的超声检查结果与1岁时运动和认知缺陷之间的关系。采用三部分异常超声检查结果分类法对脑室内出血、脑室扩大和实质病变进行分级。48名婴儿出现异常超声检查结果，其中21名有脑室内出血，18名有持续性脑室扩大，9名有实质病变。缺陷发生率如下：超声检查正常，20%；脑室内出血，33%；持续性脑室扩大，67%；实质病变，89%。本研究表明，对于出生体重小于1500克的早产新生儿以及部分出生体重超过1500克的高危新生儿，应进行系列超声检查。由于持续性脑室扩大和实质病变对1岁时运动和认知缺陷具有预测意义，因此应采用三部分异常超声检查结果分类法。
