Filicori M, Michelacci L, Ferrari P, Campaniello E, Pareschi A, Flamigni C
Am J Obstet Gynecol. 1986 Oct;155(4):768-9. doi: 10.1016/s0002-9378(86)80017-5.
In a patient with polycystic ovarian disease, low-dose intravenous pulsatile gonadotropin-releasing hormone (5 mcg every hour) and no exogenous human chorionic gonadotropin induced multiple follicular development and elevated estrogen levels and resulted in a triplet pregnancy. Patients with polycystic ovarian disease may have a higher risk of complications and should be monitored more closely during ovulation induction with pulsatile gonadotropin-releasing hormone.
在一名多囊卵巢疾病患者中,低剂量静脉注射脉冲式促性腺激素释放激素(每小时5微克)且未使用外源性人绒毛膜促性腺激素,诱发了多个卵泡发育并使雌激素水平升高,导致了三胎妊娠。多囊卵巢疾病患者可能有更高的并发症风险,在使用脉冲式促性腺激素释放激素进行促排卵治疗期间应更密切地监测。