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[单羧基纤维素及其他纤维素离子交换衍生物的抗菌作用机制]

[Mechanism of the antibacterial action of monocarboxycellulose and other ion-exchange derivatives of cellulose].

作者信息

Abaev Iu K, Kaputskiĭ V E, Adarchenko A A, Sobeshchukh O P

出版信息

Antibiot Med Biotekhnol. 1986 Aug;31(8):624-8.

PMID:3532940
Abstract

The mechanism of the antibacterial effect of monocarboxyl cellulose (MCC) and other ion exchange derivatives of cellulose was studied. It was shown that MCC, cellulose phosphate and aminocellulose had a pronounced antibacterial effect due to the presence of the ionogenic group H+ or OH- in the initial drugs. A certain role in this process was played by sorption. The level of the antibacterial activity of MCC depended on the number of the carboxylic groups. MCC is promising as a dressing material.

摘要

研究了单羧基纤维素(MCC)及纤维素的其他离子交换衍生物的抗菌作用机制。结果表明,由于初始药物中存在离子ogenic基团H⁺或OH⁻,MCC、磷酸纤维素和氨基纤维素具有显著的抗菌作用。吸附在这一过程中起到了一定作用。MCC的抗菌活性水平取决于羧基的数量。MCC作为一种敷料材料很有前景。

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