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评估特定生理流体污染物对选定中粘度聚甲基丙烯酸甲酯骨水泥力学性能的影响。

Evaluation of the Effect of Selected Physiological Fluid Contaminants on the Mechanical Properties of Selected Medium-Viscosity PMMA Bone Cements.

作者信息

Karpiński Robert, Szabelski Jakub, Krakowski Przemysław, Jojczuk Mariusz, Jonak Józef, Nogalski Adam

机构信息

Department of Machine Design and Mechatronics, Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36, 20-618 Lublin, Poland.

Section of Biomedical Engineering, Department of Computerization and Production Robotization, Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36, 20-618 Lublin, Poland.

出版信息

Materials (Basel). 2022 Mar 16;15(6):2197. doi: 10.3390/ma15062197.

DOI:10.3390/ma15062197
PMID:35329650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8951357/
Abstract

Revision surgeries several years after the implantation of the prosthesis are unfavorable from the patient's point of view as they expose him to additional discomfort, to risk of complications and are expensive. One of the factors responsible for the aseptic loosening of the prosthesis is the gradual degradation of the cement material as a result of working under considerable loads, in an aggressive environment of the human body. Contaminants present in the surgical field may significantly affect the durability of the bone cement and, consequently, of the entire bone-cement-prosthesis system. The paper presents the results of an analysis of selected mechanical properties of two medium-viscosity bone cements DePuy CMW3 Gentamicin and Heraeus Palamed, for the samples contaminated with saline and blood in the range of 1-10%. The results obtained for compressive strength and modulus of elasticity were subjected to statistical analysis, which estimated the nature of changes in these parameters depending on the amount and type of contamination and their statistical significance.

摘要

从患者的角度来看,在假体植入数年之后进行翻修手术是不利的,因为这会让患者承受额外的不适、并发症风险,而且费用高昂。假体无菌性松动的原因之一是骨水泥材料在人体具有侵蚀性的环境中承受相当大的负荷时逐渐降解。手术区域中存在的污染物可能会显著影响骨水泥的耐久性,进而影响整个骨水泥 - 假体系统的耐久性。本文展示了对两种中粘度骨水泥DePuy CMW3庆大霉素骨水泥和贺利氏Palamed骨水泥的选定力学性能进行分析的结果,这些样本被1%至10%范围内的生理盐水和血液污染。对获得的抗压强度和弹性模量结果进行了统计分析,该分析根据污染的量和类型及其统计显著性估计了这些参数的变化性质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/42b502e3c6da/materials-15-02197-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/16d77b7fd63b/materials-15-02197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/738cd9d4d53e/materials-15-02197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/c1e8b32c74bd/materials-15-02197-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/5b1231e533ea/materials-15-02197-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/b60d48449b50/materials-15-02197-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/c4e5c276ab1b/materials-15-02197-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/42b502e3c6da/materials-15-02197-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/16d77b7fd63b/materials-15-02197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/738cd9d4d53e/materials-15-02197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/c1e8b32c74bd/materials-15-02197-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/5b1231e533ea/materials-15-02197-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/b60d48449b50/materials-15-02197-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/c4e5c276ab1b/materials-15-02197-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f33/8951357/42b502e3c6da/materials-15-02197-g007.jpg

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