Feng Jingyang, Wang Ruonan, Yu Jiayi, Chen Qiuying, He Jiangnan, Zhou Hao, Du Yuchen, Liu Chen, Wang Weijun, Xu Xun, Xu Xian, Fan Ying
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China.
National Clinical Research Center for Eye Diseases, Shanghai 200080, China.
J Clin Med. 2022 Mar 14;11(6):1599. doi: 10.3390/jcm11061599.
Purpose: To investigate the characteristics of macular outward scleral height (MOSH) in different grades of myopic tractional maculopathy (MTM) and explore the risk factors for MTM. Methods: A total of 188 eyes (188 participants) with high myopia were divided into the no MTM (nMTM) group and the MTM group, which was further graded into foveoschisis, foveal detachment, full-thickness macular hole, and macular hole with retinal detachment. Swept-source optical coherence tomography was used to measure the MOSH. Results: No significant differences were found in axial length between the nMTM and MTM groups (p = 0.295). The MOSH was significantly higher in the MTM group (p < 0.001), which was identified as a risk factor for MTM (OR = 1.108, p < 0.001). The proportion of eyes with severe atrophic myopic maculopathy (AMM) was higher in the MTM group (28.48%) (p = 0.003). The macular hole with foveoschisis (MH/FS+) subgroup presented a higher average MOSH (p = 0.012) and more severe AMM (p = 0.009) than the macular hole without foveoschisis (MH/FS−) subgroup. Conclusion: MOSH would be more suitable for estimating MTM occurrence than axial length. The grading of AMM helps to evaluate the severity of MTM. The categorization of MH/FS− as a distinct grade from MH/FS+ might be preferable.
研究不同等级的近视性牵引性黄斑病变（MTM）中黄斑向外巩膜高度（MOSH）的特征，并探讨MTM的危险因素。方法：将188例高度近视患者的188只眼分为非MTM（nMTM）组和MTM组，MTM组进一步分为黄斑劈裂、黄斑脱离、全层黄斑裂孔以及黄斑裂孔伴视网膜脱离。采用扫频光学相干断层扫描测量MOSH。结果：nMTM组和MTM组的眼轴长度无显著差异（p = 0.295）。MTM组的MOSH显著更高（p < 0.001），MOSH被确定为MTM的一个危险因素（OR = 1.108，p < 0.001）。MTM组中重度萎缩性近视性黄斑病变（AMM）的眼比例更高（28.48%）（p = 0.003）。与无黄斑劈裂的黄斑裂孔（MH/FS−）亚组相比，伴有黄斑劈裂的黄斑裂孔（MH/FS+）亚组的平均MOSH更高（p = 0.012）且AMM更严重（p = 0.009）。结论：与眼轴长度相比，MOSH更适合用于估计MTM的发生。AMM的分级有助于评估MTM的严重程度。将MH/FS−与MH/FS+分类为不同等级可能更可取。
