Cheong Kai Xiong, Xu Lingqian, Ohno-Matsui Kyoko, Sabanayagam Charumathi, Saw Seang Mei, Hoang Quan V
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Surv Ophthalmol. 2022 Nov-Dec;67(6):1603-1630. doi: 10.1016/j.survophthal.2022.03.007. Epub 2022 Mar 31.
Myopic traction maculopathy (MTM), one of the complications of pathologic myopia, is a spectrum of pathological conditions that are attributed to tractional changes in the eye characterized by retinoschisis, lamellar or full thickness macular hole, and foveal retinal detachment. Considering the global public health burden of MTM and pathologic myopia, it is important to understand these sight-threatening complications and their associations. We conducted an evidence-based review of the prevalence and natural history of MTM and associated risk factors. The prevalence of MTM in the general population is low, but is increased among high myopes. MTM is associated with preretinal tractional structures, myopic refractive error and axial elongation, posterior staphyloma, dome-shaped macula, chorioretinal atrophy, and myopic macular degeneration. The clinical course of MTM tends to be stable; however, MTM may progress, resulting in visual acuity deterioration, although spontaneous improvement also occurs. The associations of MTM progression include vitreous traction, location, and extent of MTM, and lamellar macular hole-specific factors. More high-quality population-based studies that assess MTM prevalence and natural history are needed.
近视性牵引性黄斑病变(MTM)是病理性近视的并发症之一,是一系列病理状况,归因于眼部的牵引性改变,其特征为视网膜劈裂、板层或全层黄斑裂孔以及黄斑中心凹视网膜脱离。鉴于MTM和病理性近视对全球公共卫生造成的负担,了解这些威胁视力的并发症及其关联因素很重要。我们对MTM的患病率、自然病程及相关危险因素进行了循证综述。MTM在普通人群中的患病率较低,但在高度近视患者中有所增加。MTM与视网膜前牵引结构、近视屈光不正和眼轴延长、后巩膜葡萄肿、穹窿状黄斑、脉络膜视网膜萎缩以及近视性黄斑变性有关。MTM的临床病程往往较为稳定;然而,MTM可能会进展,导致视力下降,不过也会出现自发改善的情况。MTM进展的相关因素包括玻璃体牵引、MTM的位置和范围,以及板层黄斑裂孔的特定因素。需要更多基于高质量人群的研究来评估MTM的患病率和自然病程。