• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

中心性软性玻璃膜疣完全消退,无地图样萎缩或脉络膜新生血管形成。

Complete Resolution of Central Soft Drusen without Geographic Atrophy or Choroidal Neovascularization.

作者信息

Zeng Rebecca, Garg Itika, Miller John B

机构信息

Harvard Retinal Imaging Lab, Boston, MA 02114, USA.

Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA.

出版信息

J Clin Med. 2022 Mar 16;11(6):1637. doi: 10.3390/jcm11061637.

DOI:10.3390/jcm11061637
PMID:35329963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8951140/
Abstract

The treatment and prevention of dry age-related macular degeneration (AMD) traditionally involve lifestyle modifications and antioxidant supplementation, including the AREDS2 formula. We present a case of a woman with dry AMD in her right eye with several large, confluent central drusen on her exam and optical coherence tomography B-scan. Over the course of a year, the drusen almost completely disappeared, but the retinal layers were preserved without the development of geographic atrophy or choroidal neovascularization. While the exact cause of this phenomenon is unclear, it was thought to be associated with this patient's strict daily use of numerous dietary supplements. This case highlights the potential in exploring alternative medicine supplements in the treatment of AMD.

摘要

传统上,干性年龄相关性黄斑变性(AMD)的治疗和预防包括生活方式的改变以及抗氧化剂补充,其中包括年龄相关性眼病研究2(AREDS2)配方。我们报告一例右眼患有干性AMD的女性病例,其检查和光学相干断层扫描B扫描显示有几个大的、融合的中央玻璃膜疣。在一年的时间里,玻璃膜疣几乎完全消失,视网膜各层得以保留,未出现地图样萎缩或脉络膜新生血管形成。虽然这种现象的确切原因尚不清楚,但据认为与该患者严格每日服用多种膳食补充剂有关。该病例凸显了探索替代医学补充剂治疗AMD的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dbf/8951140/09a32b05cbff/jcm-11-01637-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dbf/8951140/c5779def56fd/jcm-11-01637-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dbf/8951140/09a32b05cbff/jcm-11-01637-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dbf/8951140/c5779def56fd/jcm-11-01637-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dbf/8951140/09a32b05cbff/jcm-11-01637-g002.jpg

相似文献

1
Complete Resolution of Central Soft Drusen without Geographic Atrophy or Choroidal Neovascularization.中心性软性玻璃膜疣完全消退,无地图样萎缩或脉络膜新生血管形成。
J Clin Med. 2022 Mar 16;11(6):1637. doi: 10.3390/jcm11061637.
2
Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration.光学相干断层扫描反射性玻璃膜疣亚结构预测年龄相关性黄斑变性进展为地图状萎缩
Ophthalmology. 2016 Dec;123(12):2554-2570. doi: 10.1016/j.ophtha.2016.08.047. Epub 2016 Oct 25.
3
Influence of vitrectomy on the progression of dry age-related macular degeneration.玻璃体切除术对干性年龄相关性黄斑变性进展的影响。
Graefes Arch Clin Exp Ophthalmol. 2021 Apr;259(4):847-853. doi: 10.1007/s00417-020-04943-x. Epub 2020 Oct 16.
4
Prevalence and significance of subretinal drusenoid deposits (reticular pseudodrusen) in age-related macular degeneration.年龄相关性黄斑变性中视网膜下类 drusen 样沉积物(网状假性 drusen)的患病率和意义。
Ophthalmology. 2010 Sep;117(9):1775-81. doi: 10.1016/j.ophtha.2010.01.027. Epub 2010 May 15.
5
Spectral domain optical coherence tomography imaging of dry age-related macular degeneration.干性年龄相关性黄斑变性的光谱域光学相干断层扫描成像
Ophthalmic Surg Lasers Imaging. 2010 Nov-Dec;41 Suppl:S6-S14. doi: 10.3928/15428877-20101031-19.
6
Age-related macular degeneration and risk factors for the development of choroidal neovascularisation in the fellow eye: a 3-year follow-up study.年龄相关性黄斑变性及对侧眼脉络膜新生血管发生的危险因素:一项 3 年随访研究。
Ophthalmologica. 2011;226(3):110-8. doi: 10.1159/000329473. Epub 2011 Aug 3.
7
Drusen Volume and Retinal Pigment Epithelium Abnormal Thinning Volume Predict 2-Year Progression of Age-Related Macular Degeneration.玻璃膜疣体积和视网膜色素上皮异常变薄体积可预测年龄相关性黄斑变性的 2 年进展。
Ophthalmology. 2016 Jan;123(1):39-50.e1. doi: 10.1016/j.ophtha.2015.09.016. Epub 2015 Nov 12.
8
Spectral-domain optical coherence tomography characteristics of intermediate age-related macular degeneration.光谱域光相干断层扫描在年龄相关性中间型黄斑变性中的特征。
Ophthalmology. 2013 Jan;120(1):140-50. doi: 10.1016/j.ophtha.2012.07.004. Epub 2012 Sep 8.
9
Choriocapillaris changes in dry age-related macular degeneration and geographic atrophy: a review.干性年龄相关性黄斑变性和地图样萎缩中的脉络膜毛细血管变化:综述
Eye Vis (Lond). 2018 Sep 15;5:22. doi: 10.1186/s40662-018-0118-x. eCollection 2018.
10
Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.年龄相关性眼病研究1和2中膳食营养素摄入量与晚期年龄相关性黄斑变性进展情况
Ophthalmology. 2021 Mar;128(3):425-442. doi: 10.1016/j.ophtha.2020.08.018. Epub 2020 Aug 25.

引用本文的文献

1
Biomarkers for the Progression of Intermediate Age-Related Macular Degeneration.中年年龄相关性黄斑变性进展的生物标志物
Ophthalmol Ther. 2023 Dec;12(6):2917-2941. doi: 10.1007/s40123-023-00807-9. Epub 2023 Sep 29.

本文引用的文献

1
Curcuma-Based Nutritional Supplement in Patients with Neovascular Age-Related Macular Degeneration.基于姜黄的营养补充剂治疗新生血管性年龄相关性黄斑变性。
J Med Food. 2021 Nov;24(11):1191-1196. doi: 10.1089/jmf.2020.0199. Epub 2021 Apr 19.
2
Subthreshold laser treatment for reticular pseudodrusen secondary to age-related macular degeneration.年龄相关性黄斑变性的网状假性色素上皮营养不良的亚阈激光治疗。
Sci Rep. 2021 Jan 26;11(1):2193. doi: 10.1038/s41598-021-81810-7.
3
Laser and anti-vascular endothelial growth factor treatment for drusenoid pigment epithelial detachment in age-related macular degeneration.
激光和抗血管内皮生长因子治疗年龄相关性黄斑变性的渗出性色素上皮脱离。
Sci Rep. 2020 Sep 1;10(1):14370. doi: 10.1038/s41598-020-71401-3.
4
Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.年龄相关性眼病研究1和2中膳食营养素摄入量与晚期年龄相关性黄斑变性进展情况
Ophthalmology. 2021 Mar;128(3):425-442. doi: 10.1016/j.ophtha.2020.08.018. Epub 2020 Aug 25.
5
Orally Administered Alpha Lipoic Acid as a Treatment for Geographic Atrophy: A Randomized Clinical Trial.口服硫辛酸治疗地图状萎缩:一项随机临床试验。
Ophthalmol Retina. 2020 Sep;4(9):889-898. doi: 10.1016/j.oret.2020.03.019. Epub 2020 Apr 2.
6
Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights.虾青素在眼部疾病治疗中的临床应用:新的见解。
Mar Drugs. 2020 May 1;18(5):239. doi: 10.3390/md18050239.
7
Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases.维生素 K 作为饮食补充剂对人类健康的影响:与年龄相关疾病相关的最新证据。
Nutrients. 2020 Jan 3;12(1):138. doi: 10.3390/nu12010138.
8
N-Acetyl-L-cysteine Protects Human Retinal Pigment Epithelial Cells from Oxidative Damage: Implications for Age-Related Macular Degeneration.N-乙酰-L-半胱氨酸可保护人视网膜色素上皮细胞免受氧化损伤:与年龄相关性黄斑变性有关。
Oxid Med Cell Longev. 2019 Aug 14;2019:5174957. doi: 10.1155/2019/5174957. eCollection 2019.
9
Injectable taurine-loaded alginate hydrogels for retinal pigment epithelium (RPE) regeneration.用于视网膜色素上皮(RPE)再生的可注射牛磺酸负载的藻酸盐水凝胶。
Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109787. doi: 10.1016/j.msec.2019.109787. Epub 2019 May 23.
10
Nutrients for Prevention of Macular Degeneration and Eye-Related Diseases.预防黄斑变性及眼相关疾病的营养素
Antioxidants (Basel). 2019 Apr 2;8(4):85. doi: 10.3390/antiox8040085.