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外周动脉疾病运动表现的体能-疲劳模型:无痛运动计划的预测和实测效果

A Fitness-Fatigue Model of Performance in Peripheral Artery Disease: Predicted and Measured Effects of a Pain-Free Exercise Program.

作者信息

Lamberti Nicola, Piva Giovanni, Businaro Federico, Caruso Lorenzo, Crepaldi Anna, Lòpez-Soto Pablo Jesùs, Manfredini Fabio

机构信息

Department of Neuroscience and Rehabilitation, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.

PhD Program in Environmental Sustainability and Wellbeing, Department of Humanistic Studies, University of Ferrara, 44121 Ferrara, Italy.

出版信息

J Pers Med. 2022 Mar 4;12(3):397. doi: 10.3390/jpm12030397.

DOI:10.3390/jpm12030397
PMID:35330397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8949585/
Abstract

Banister impulse-response (IR) model estimates the performance in response to the training impulses (TRIMPs). In 100 patients with peripheral artery disease (PAD), we tested by an IR model the predictability of the effects of a 6-month structured home-based exercise program. The daily TRIMPs obtained from prescribed walking speed, relative intensity and time of exercise determined the fitness-fatigue components of performance. The estimated performance values, calculated from the baseline 6-min and pain-free walking distance (6MWD and PFWD, respectively) were compared with values measured at visits through regression models. Interval pain-free walking at controlled speed prescribed during circa-monthly hospital visits (5 ± 1) was safely performed at home with good adherence (92% of scheduled sessions, 144 ± 25 km walked in 50 ± 8 training hours). The mean TRIMP rose throughout the program from 276 to 601 a.u. The measured 6MWD and PFWD values increased (+33 m and +121 m, respectively) showing a good fit with those estimated by the IR model (6MWD: R 0.81; PFWD: R 0.68) and very good correspondence (correlation coefficients: 0.91 to 0.95), without sex differences. The decay of performance without training was estimated at 18 ± 3 weeks. In PAD, an IR model predicted the walking performance following a pain-free exercise program. IR models may contribute to design and verify personalized training programs.

摘要

巴尼斯特脉冲响应(IR)模型可估计对训练脉冲(TRIMPs)的反应性能。在100例外周动脉疾病(PAD)患者中,我们通过IR模型测试了一项为期6个月的结构化居家锻炼计划效果的可预测性。从规定的步行速度、相对强度和锻炼时间得出的每日TRIMPs决定了性能的健康 - 疲劳组成部分。根据基线6分钟步行距离和无痛步行距离(分别为6MWD和PFWD)计算得出的估计性能值,通过回归模型与随访时测量的值进行比较。在大约每月一次的医院就诊期间规定的控制速度下进行的间歇性无痛步行(5±1),在居家时安全地进行,依从性良好(占计划疗程的92%,在50±8个训练小时内步行144±25公里)。整个计划中,平均TRIMP从276任意单位升至601任意单位。测量的6MWD和PFWD值增加(分别增加33米和121米),与IR模型估计的值拟合良好(6MWD:R 0.81;PFWD:R 0.68),且对应性非常好(相关系数:0.91至0.95),无性别差异。未进行训练时性能的衰减估计为18±3周。在PAD中,IR模型可预测无痛锻炼计划后的步行性能。IR模型可能有助于设计和验证个性化训练计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210d/8949585/9795971f3f82/jpm-12-00397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210d/8949585/322631e5f109/jpm-12-00397-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210d/8949585/9795971f3f82/jpm-12-00397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210d/8949585/322631e5f109/jpm-12-00397-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210d/8949585/9795971f3f82/jpm-12-00397-g002.jpg

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2
Effectiveness of blood flow-restricted slow walking on mobility in severe multiple sclerosis: A pilot randomized trial.血流限制式慢走对严重多发性硬化症患者移动能力的有效性:一项初步随机试验。
Scand J Med Sci Sports. 2020 Oct;30(10):1999-2009. doi: 10.1111/sms.13764. Epub 2020 Jul 25.
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Biomarkers of Muscle Metabolism in Peripheral Artery Disease: A Dynamic NIRS-Assisted Study to Detect Adaptations Following Revascularization and Exercise Training.
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Diagnostics (Basel). 2020 May 16;10(5):312. doi: 10.3390/diagnostics10050312.
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Meaningful change in 6-minute walk in people with peripheral artery disease.周围动脉疾病患者 6 分钟步行距离的有意义变化。
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