Kwon Young Suk, Lee Sang-Hwa, Kim Chulho, Yu Hyunjae, Sohn Jong-Hee, Lee Jae Jun, Kim Dong-Kyu
Division of Big Data and Artificial Intelligence, Institute of New Frontier Research, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24253, Korea.
Department of Anesthesiology and Pain Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24253, Korea.
J Pers Med. 2022 Mar 15;12(3):468. doi: 10.3390/jpm12030468.
The relationship between dementia and surgery remains unclear. Research to elucidate the relationship between them is scarce, and conducting epidemiological research is complicated. This study aimed to investigate the incidence and risk of dementia according to the surgery type. We performed a retrospective propensity score-matched cohort study using nationwide representative cohort sample data from the Korean National Health Insurance Service in South Korea between 2003 and 2004. Incidence rates for dementia were obtained by dividing the number of patients with dementia by person-years at risk. To identify the risk of dementia according to the type of surgery, we investigated the hazard ratio by each surgery type. The incidence rates of dementia in control, musculoskeletal, and two or more surgeries groups were 9.66, 13.47, and 13.36 cases per 1000 person-years, respectively. The risk of dementia in the musculoskeletal and two or more surgeries groups was 1.44-fold higher (95% confidence interval (95% CI), 1.22-1.70) and 1.42-fold higher (95% CI, 1.17-1.72) than that in the control group, respectively. Patients who underwent musculoskeletal surgery and two or more surgeries had a higher risk of dementia; however, there was no association with the type of anesthesia administered.
痴呆症与手术之间的关系仍不明确。阐明它们之间关系的研究很少，而且进行流行病学研究很复杂。本研究旨在根据手术类型调查痴呆症的发病率和风险。我们利用2003年至2004年韩国国民健康保险服务中心全国代表性队列样本数据进行了一项回顾性倾向评分匹配队列研究。痴呆症发病率通过将痴呆症患者人数除以风险人年数得出。为了根据手术类型确定痴呆症风险，我们调查了每种手术类型的风险比。对照组、肌肉骨骼手术组和两种或更多种手术组的痴呆症发病率分别为每1000人年9.66例、13.47例和13.36例。肌肉骨骼手术组和两种或更多种手术组患痴呆症的风险分别比对照组高1.44倍（95%置信区间（95%CI），1.22 - 1.70）和1.42倍（95%CI，1.17 - 1.72）。接受肌肉骨骼手术和两种或更多种手术的患者患痴呆症的风险更高；然而，这与所使用的麻醉类型无关。
