Min Chan-Yang, Lee Jung-Woo, Kwon Bong-Cheol, Kwon Mi-Jung, Kim Ji-Hee, Kim Joo-Hee, Bang Woo-Jin, Choi Hyo-Geun
Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14066, Korea.
Department of Orthopaedic Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Korea.
J Pers Med. 2022 Mar 18;12(3):491. doi: 10.3390/jpm12030491.
The purpose of our study was to examine the occurrence of osteoporotic fractures (fxs) according to the level of physical activity (PA) among osteoporosis using the Korean National Health Insurance Service (NHIS) customized database. From NHIS data from 2009 to 2017, osteoporosis was selected as requested. PA was classified into 'high PA' ( = 58,620), 'moderate PA' ( = 58,620), and 'low PA' ( = 58,620) and were matched in a 1:1:1 ratio by gender, age, income within the household unit, and region of residence. A stratified Cox proportional hazard model was used to calculate hazard ratios (HRs) for each type of fx comparing PA groups. The 'low PA' group was the reference group. For vertebral fx, the adjusted HR (95% confidence intervals (CIs)) was 0.27 (0.26-0.28) for the 'high PA' group and 0.43 (0.42-0.44) for the 'moderate PA' group. For hip fx, the adjusted HR (95% CIs) was 0.37 (0.34-0.40) for the 'high PA' group and 0.51 (0.47-0.55) for the 'moderate PA' group. For distal radius fx, the adjusted HR (95% CIs) was 0.32 (0.30-0.33) for the 'high PA' group and 0.46 (0.45-0.48) for the 'moderate PA' group. The results of this study suggest that a higher intensity of PA is associated with a lower risk of osteoporotic fxs, including vertebral fx, hip fx, and distal radius fx.
我们研究的目的是利用韩国国民健康保险服务（NHIS）定制数据库，根据骨质疏松症患者的身体活动（PA）水平，研究骨质疏松性骨折（fxs）的发生情况。从2009年至2017年的NHIS数据中，按要求选取骨质疏松症患者。PA分为“高PA”（=58,620）、“中PA”（=58,620）和“低PA”（=58,620），并按性别、年龄、家庭单位收入和居住地区以1:1:1的比例进行匹配。采用分层Cox比例风险模型计算各PA组与每种骨折类型相比的风险比（HRs）。“低PA”组作为参照组。对于椎体骨折，“高PA”组的调整后HR（95%置信区间（CIs））为0.27（0.26 - 0.28），“中PA”组为0.43（0.42 - 0.44）。对于髋部骨折，“高PA”组的调整后HR（95% CIs）为0.37（0.34 - 0.40），“中PA”组为0.51（0.47 - 0.55）。对于桡骨远端骨折，“高PA”组的调整后HR（95% CIs）为0.32（0.30 - 0.33），“中PA”组为0.46（0.45 - 0.48）。本研究结果表明，较高强度的PA与较低的骨质疏松性骨折风险相关，包括椎体骨折、髋部骨折和桡骨远端骨折。
