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体力活动、日照时长与骨质疏松性骨折:一项巢式病例对照研究。

Physical Activity, Sunshine Duration, and Osteoporotic Fractures: A Nested Case-Control Study.

作者信息

Min Chanyang, Yoo Dae-Myoung, Kwon Mi-Jung, Kim Joo-Hee, Choi Hyo-Geun

机构信息

Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea.

Department of Pathology, Hallym Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.

出版信息

J Pers Med. 2022 Jan 26;12(2):164. doi: 10.3390/jpm12020164.

DOI:10.3390/jpm12020164
PMID:35207652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8878966/
Abstract

This study examined the associations between the occurrence of osteoporotic fractures in detailed sites and combined physical activity (PA) and sunshine duration (SD). Data from the Korean National Health Insurance Service-National Health Screening Cohort for 7-year periods and from the Korea Meteorological Administration were used. Osteoporotic fractures ( = 12,103), including vertebral fractures, hip fractures, and distal radius fractures, and matched controls ( = 24,206) were selected in 1:2 ratios by age, sex, income, and region of residence. PA was classified as moderate- to high-intensity PA (High PA) and low-intensity PA (Low PA). SD was classified as Short SD (<6.1 h) and Long SD (≥6.1 h). Conditional logistic regression was used to calculate the odds ratios (ORs) with 95%-confidence intervals (CIs) of the combined PA and SD groups for the occurrence of each osteoporotic fracture. Compared to 'Low PA + Short SD', the adjusted ORs (95% CIs) for vertebral fracture in 'High PA + Short SD' and 'High PA + Long SD' were 0.83 (0.76-0.91) and 0.84 (0.77-0.92), respectively. Hip/distal radius fractures were not associated with the combined PA and SD group. We suggest that a higher intensity of PA is inversely associated with the risk of vertebral fracture.

摘要

本研究调查了特定部位骨质疏松性骨折的发生与综合体力活动(PA)及日照时长(SD)之间的关联。研究使用了韩国国民健康保险服务中心全国健康筛查队列7年的数据以及韩国气象厅的数据。按年龄、性别、收入和居住地区以1:2的比例选取了包括椎体骨折、髋部骨折和桡骨远端骨折在内的骨质疏松性骨折患者(n = 12,103)及匹配的对照组(n = 24,206)。PA分为中高强度PA(高PA)和低强度PA(低PA)。SD分为短日照(<6.1小时)和长日照(≥6.1小时)。采用条件逻辑回归计算各骨质疏松性骨折发生时PA和SD组合组的比值比(OR)及95%置信区间(CI)。与“低PA + 短日照”相比,“高PA + 短日照”和“高PA + 长日照”中椎体骨折的校正OR(95%CI)分别为0.83(0.76 - 0.91)和0.84(0.77 - 0.92)。髋部/桡骨远端骨折与PA和SD组合组无关。我们认为较高强度的PA与椎体骨折风险呈负相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b903/8878966/c31b36d3be5c/jpm-12-00164-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b903/8878966/c31b36d3be5c/jpm-12-00164-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b903/8878966/c31b36d3be5c/jpm-12-00164-g001.jpg

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