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Cellular and molecular pharmacology of auranofin and related gold complexes.

作者信息

Crooke S T, Snyder R M, Butt T R, Ecker D J, Allaudeen H S, Monia B, Mirabelli C K

出版信息

Biochem Pharmacol. 1986 Oct 15;35(20):3423-31. doi: 10.1016/0006-2952(86)90608-8.

DOI:10.1016/0006-2952(86)90608-8
PMID:3533080
Abstract
摘要

相似文献

1
Cellular and molecular pharmacology of auranofin and related gold complexes.金诺芬及相关金配合物的细胞与分子药理学
Biochem Pharmacol. 1986 Oct 15;35(20):3423-31. doi: 10.1016/0006-2952(86)90608-8.
2
Cellular interactions of auranofin and a related gold complex with RAW 264.7 macrophages.金诺芬及一种相关金络合物与RAW 264.7巨噬细胞的细胞相互作用。
Biochem Pharmacol. 1987 Mar 1;36(5):647-54. doi: 10.1016/0006-2952(87)90715-5.
3
Synthesis of thionato(triethylphosphine) gold(I) complexes:analogues of "auranofin," an antiarthritic drug.
J Inorg Biochem. 1990 Feb;38(2):95-100. doi: 10.1016/0162-0134(90)84017-j.
4
The cellular and molecular pharmacology of auranofin and related gold complexes.
Scand J Rheumatol Suppl. 1986;63:1-18.
5
The comparative toxicity of gold salts.金盐的相对毒性。
J Rheumatol Suppl. 1982 Jul-Aug;8:79-80.
6
Control of intra- and extra-cellular sulphydryl-disulphide balances with gold phosphine drugs: 31P nuclear magnetic resonance studies of human blood.
J Inorg Biochem. 1980 Jul;12(4):317-22. doi: 10.1016/s0162-0134(00)80272-x.
7
Effect of auranofin and other gold complexes on the activity of phospholipase C.金诺芬及其他金配合物对磷脂酶C活性的影响。
Mol Pharmacol. 1987 Sep;32(3):437-42.
8
Gold complexes in the treatment of rheumatoid arthritis.
Met Ions Biol Syst. 2004;41:279-304.
9
(13)C, (31)P and (15)N NMR studies of the ligand exchange reactions of auranofin and chloro(triethylphosphine)gold(I) with thiourea.用(13)C、(31)P和(15)N核磁共振研究金诺芬和氯(三乙膦)金(I)与硫脲的配体交换反应。
J Inorg Biochem. 2002 Jan 1;88(1):44-52. doi: 10.1016/s0162-0134(01)00305-1.
10
31P nuclear-magnetic-resonance studies at 24 and 162 MHz of blood containing an anti-arthritic gold phosphine: relaxation via chemical-shift anisotropy.在24兆赫和162兆赫下对含有抗关节炎金膦的血液进行的31P核磁共振研究:通过化学位移各向异性实现弛豫。
Biochem Soc Trans. 1980 Oct;8(5):635-6. doi: 10.1042/bst0080635a.

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Inhibition of Thioredoxin-Reductase by Auranofin as a Pro-Oxidant Anticancer Strategy for Glioblastoma: In Vitro and In Vivo Studies.金诺芬对硫氧还蛋白还原酶的抑制作用作为胶质母细胞瘤的促氧化抗癌策略:体外和体内研究
Int J Mol Sci. 2025 Feb 27;26(5):2084. doi: 10.3390/ijms26052084.
2
Optimization of the Solvent and In Vivo Administration Route of Auranofin in a Syngeneic Non-Small Cell Lung Cancer and Glioblastoma Mouse Model.金诺芬在同基因非小细胞肺癌和胶质母细胞瘤小鼠模型中的溶剂及体内给药途径优化
Pharmaceutics. 2022 Dec 9;14(12):2761. doi: 10.3390/pharmaceutics14122761.
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Speciation Analysis Highlights the Interactions of Auranofin with the Cytoskeleton Proteins of Lung Cancer Cells.
形态分析揭示了金诺芬与肺癌细胞细胞骨架蛋白的相互作用。
Pharmaceuticals (Basel). 2022 Oct 19;15(10):1285. doi: 10.3390/ph15101285.
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The gold complex auranofin: new perspectives for cancer therapy.金络合物金诺芬:癌症治疗的新视角。
Discov Oncol. 2021 Oct 20;12(1):42. doi: 10.1007/s12672-021-00439-0.
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Metal-Dependent Cytotoxic and Kinesin Spindle Protein Inhibitory Activity of Ru, Os, Rh, and Ir Half-Sandwich Complexes of Ispinesib-Derived Ligands.基于异长春花碱衍生配体的 Ru、Os、Rh 和 Ir 半三明治配合物的金属依赖性细胞毒性和驱动蛋白纺锤体蛋白抑制活性。
Inorg Chem. 2020 Oct 19;59(20):14879-14890. doi: 10.1021/acs.inorgchem.0c00957. Epub 2020 Oct 1.
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Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development.肌生成相关 miRNA 对 JNK/MAPK 信号通路的抑制作用是骨骼肌发育所必需的。
Cell Death Differ. 2018 Sep;25(9):1581-1597. doi: 10.1038/s41418-018-0063-1. Epub 2018 Feb 15.
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Inhibition by anti-inflammatory agents of contraction induced by epidermal growth factor-urogastrone in isolated longitudinal smooth muscle strips from guinea-pig stomach.抗炎药对表皮生长因子-尿抑胃素诱导的豚鼠胃离体纵行平滑肌条收缩的抑制作用。
Br J Pharmacol. 1988 Nov;95(3):821-9. doi: 10.1111/j.1476-5381.1988.tb11710.x.
8
Auranofin modulates human neutrophil superoxide production and protein phosphorylation.金诺芬调节人类中性粒细胞超氧化物生成和蛋白质磷酸化。
Rheumatol Int. 1989;8(6):245-50. doi: 10.1007/BF00270979.
9
Induction of macrophage plasminogen activator by asbestos is independent of PKC activation.石棉诱导巨噬细胞纤溶酶原激活剂与蛋白激酶C激活无关。
Arch Toxicol. 1991;65(5):386-9. doi: 10.1007/BF02284261.
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Immunomodulatory effects of therapeutic gold compounds. Gold sodium thiomalate inhibits the activity of T cell protein kinase C.治疗性金化合物的免疫调节作用。硫代苹果酸金钠抑制T细胞蛋白激酶C的活性。
J Clin Invest. 1992 Jun;89(6):1839-48. doi: 10.1172/JCI115788.